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Arofylline

Name: Arofylline
Brand: TargetMol
SKU: T9816
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T9816Cas No. 136145-07-8

Alias LAS 31025

Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.

Arofylline

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Purity: 98.19%

Catalog No. T9816Alias LAS 31025Cas No. 136145-07-8

Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$195	In Stock	In Stock
5 mg	$437	-	In Stock
10 mg	$646	-	In Stock
25 mg	$987	-	In Stock
50 mg	$1,380	-	In Stock
1 mL x 10 mM (in DMSO)	$431	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Batch Information

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Purity:98.19%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Arofylline (LAS 31025) is a PDE4 inhibitor and can be used for asthma studies.
Synonyms	LAS 31025

Chemical Properties

Molecular Weight	304.73
Formula	C₁₄H₁₃ClN₄O₂
Cas No.	136145-07-8
Smiles	O=C1N(C2=C(C(=O)N1CCC)NC=N2)C3=CC=C(Cl)C=C3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (180.49 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.2816 mL	16.4080 mL	32.8159 mL	164.0797 mL
5 mM	0.6563 mL	3.2816 mL	6.5632 mL	32.8159 mL
10 mM	0.3282 mL	1.6408 mL	3.2816 mL	16.4080 mL
20 mM	0.1641 mL	0.8204 mL	1.6408 mL	8.2040 mL
50 mM	0.0656 mL	0.3282 mL	0.6563 mL	3.2816 mL
100 mM	0.0328 mL	0.1641 mL	0.3282 mL	1.6408 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc