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BML-259
🥰Excellent
Catalog No. T36964Cas No. 267654-00-2
Alias CAY10554
BML-259 is an inhibitor of CDK5 and CDK2 with IC50s of 64 and 98 nM, respectively. BML-259 can be used in studies about the treatment of cancer and neurodegenerative diseases.
BML-259
🥰Excellent
Purity: 99.84%
Catalog No. T36964Alias CAY10554Cas No. 267654-00-2
BML-259 is an inhibitor of CDK5 and CDK2 with IC50s of 64 and 98 nM, respectively. BML-259 can be used in studies about the treatment of cancer and neurodegenerative diseases.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 5 mg | $43 | - | In Stock | |
| 10 mg | $77 | - | In Stock | |
| 25 mg | $172 | - | In Stock | |
| 50 mg | $293 | - | In Stock | |
| 100 mg | $513 | - | In Stock | |
| 500 mg | $1,090 | - | In Stock | |
| 1 mL x 10 mM (in DMSO) | $48 | - | In Stock |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.84%
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Product Introduction
Bioactivity
Chemical Properties
| Description | BML-259 is an inhibitor of CDK5 and CDK2 with IC50s of 64 and 98 nM, respectively. BML-259 can be used in studies about the treatment of cancer and neurodegenerative diseases. |
| In vitro | BML-259 prevents a large population of cells from NAC-evoked cell death[1]. |
| Synonyms | CAY10554 |
| Molecular Weight | 260.35 |
| Formula | C14H16N2OS |
| Cas No. | 267654-00-2 |
| Smiles | CC(C)c1cnc(NC(=O)Cc2ccccc2)s1 |
| Relative Density. | no data available |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature. |
| Solubility Information | DMSO:PBS (pH 7.2)(1:2): 0.3 mg/mL (1.15 mM), Sonication is recommended. DMF: 30 mg/mL (115.23 mM), Sonication is recommended. DMSO: 120 mg/mL (460.92 mM), Sonication is recommended. Ethanol: 0.25 mg/mL (0.96 mM), Sonication is recommended. |
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In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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