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Mc-MMAD is monomethyl auristatin D (MMAD) modified with the protective group maleimidocaproyl (Mc). MMAD is a potent tubulin microtubule inhibitor that suppresses cancer cell proliferation and is commonly employed as a toxic payload in ADC synthesis.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $98 | In Stock | |
5 mg | $243 | In Stock | |
10 mg | $388 | In Stock | |
25 mg | $639 | In Stock | |
50 mg | $898 | In Stock | |
100 mg | $1,190 | In Stock |
Description | Mc-MMAD is monomethyl auristatin D (MMAD) modified with the protective group maleimidocaproyl (Mc). MMAD is a potent tubulin microtubule inhibitor that suppresses cancer cell proliferation and is commonly employed as a toxic payload in ADC synthesis. |
Molecular Weight | 964.26 |
Formula | C51H77N7O9S |
Cas No. | 1401963-15-2 |
Smiles | [H][C@]([C@@H](C)CC)([C@@H](CC(=O)N1CCC[C@H]1[C@H](OC)[C@@H](C)C(=O)N[C@@H](Cc1ccccc1)c1nccs1)OC)N(C)C(=O)[C@@H](NC(=O)[C@H](C(C)C)N(C)C(=O)CCCCCN1C(=O)C=CC1=O)C(C)C |
Relative Density. | 1.168 g/cm3 (Predicted) |
Color | White |
Appearance | Solid |
Storage | The compound is unstable in solution. Please use soon | Powder: -20°C for 3 years | Shipping with blue ice/Shipping at ambient temperature. |
Solubility Information | DMSO: ≥ 80 mg/mL, Sonication is recommended. |
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