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Mc-MMAD

Name: Mc-MMAD
Brand: TargetMol
SKU: T18311
Rating: 4.5 (1 reviews)

🥰Excellent

Catalog No. T18311Cas No. 1401963-15-2

Mc-MMAD, a drug-linker conjugate for antibody-drug conjugates (ADCs), incorporates the protective group maleimidocaproyl (Mc) conjugated to monomethyl auristatin D (MMAD), a potent inhibitor of tubulin.

Mc-MMAD

🥰Excellent

Purity: 98.04%

Catalog No. T18311Cas No. 1401963-15-2

Pack Size	Price	Availability	Quantity
100 mg	Inquiry	In Stock
500 mg	Inquiry	In Stock

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:98.04%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description

Chemical Properties

Molecular Weight	964.26
Formula	C₅₁H₇₇N₇O₉S
Cas No.	1401963-15-2
Relative Density.	1.168 g/cm3 (Predicted)
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 100 mg/mL (103.71 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.0371 mL	5.1853 mL	10.3706 mL	51.8532 mL
5 mM	0.2074 mL	1.0371 mL	2.0741 mL	10.3706 mL
10 mM	0.1037 mL	0.5185 mL	1.0371 mL	5.1853 mL
20 mM	0.0519 mL	0.2593 mL	0.5185 mL	2.5927 mL
50 mM	0.0207 mL	0.1037 mL	0.2074 mL	1.0371 mL
100 mM	0.0104 mL	0.0519 mL	0.1037 mL	0.5185 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc