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Radezolid

Name: Radezolid
Brand: TargetMol
SKU: T16718
Price: 48 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T16718Cas No. 869884-78-6

Alias RX-1741

Radezolid (RX-1741) is a novel oxazolidinone antibiotic.

Radezolid

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Purity: 97.52%

Catalog No. T16718Alias RX-1741Cas No. 869884-78-6

Radezolid (RX-1741) is a novel oxazolidinone antibiotic.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$48	In Stock	In Stock
5 mg	$113	In Stock	In Stock
10 mg	$197	In Stock	In Stock
25 mg	$357	In Stock	In Stock
50 mg	$553	In Stock	In Stock
100 mg	$788	-	In Stock
1 mL x 10 mM (in DMSO)	$126	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:97.52%

Appearance:Solid

Color:Yellow

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Radezolid (RX-1741) is a novel oxazolidinone antibiotic.
In vitro	Radezolid consistently demonstrates superior potency to linezolid across all tested bacteria, maintaining this advantage regardless of the bacterium's sensitivity, when the concentration measurements are standardized to weight (mg/L). This is evidenced by Radezolid's MIC values, which are always equal to or lower than those of linezolid—by up to 3 log2 dilutions—for strains susceptible to linezolid, and exhibit an 8-fold potency increase against linezolid-resistant strains. Additionally, Radezolid, alongside TR-700, is effective against mutants with 3-copy alterations at G2447T, G2576T, and G2576T/T2571C positions [1][2].
Synonyms	RX-1741

Chemical Properties

Molecular Weight	438.45
Formula	C₂₂H₂₃FN₆O₃
Cas No.	869884-78-6
Smiles	CC(=O)NC[C@H]1CN(C(=O)O1)c1ccc(c(F)c1)-c1ccc(CNCc2cnn[nH]2)cc1
Relative Density.	1.31g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 35.07 mg/mL (79.99 mM), Sonication and heating are recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.56 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.2808 mL	11.4038 mL	22.8076 mL	114.0381 mL
5 mM	0.4562 mL	2.2808 mL	4.5615 mL	22.8076 mL
10 mM	0.2281 mL	1.1404 mL	2.2808 mL	11.4038 mL
20 mM	0.1140 mL	0.5702 mL	1.1404 mL	5.7019 mL
50 mM	0.0456 mL	0.2281 mL	0.4562 mL	2.2808 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc