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BSc5367

🥰Excellent
Catalog No. T201389Cas No. 3029584-84-4
Alias BSc 5367

BSc5367 is a potent inhibitor of the structural domain of Nek1 kinase with an IC50=11.5 nM. Nek1 is a NIMA-associated protein kinase tightly linked to cell cycle regulation, DNA repair, and microtubule regulation. BSc5367 can be used in studies related to amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD), and several types of radiotherapy-resistant cancers.

BSc5367

BSc5367

🥰Excellent
Purity: 98.72%
Catalog No. T201389Alias BSc 5367Cas No. 3029584-84-4
BSc5367 is a potent inhibitor of the structural domain of Nek1 kinase with an IC50=11.5 nM. Nek1 is a NIMA-associated protein kinase tightly linked to cell cycle regulation, DNA repair, and microtubule regulation. BSc5367 can be used in studies related to amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD), and several types of radiotherapy-resistant cancers.
Pack SizePriceAvailabilityQuantity
1 mg$98 In Stock
5 mg$178 In Stock
10 mg$283 In Stock
25 mg$595 In Stock
50 mg$923 In Stock
100 mg$1,438 In Stock
1 mL x 10 mM (in DMSO)$195 In Stock
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Purity:98.72%
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Product Introduction

Bioactivity
Description
BSc5367 is a potent inhibitor of the structural domain of Nek1 kinase with an IC50=11.5 nM. Nek1 is a NIMA-associated protein kinase tightly linked to cell cycle regulation, DNA repair, and microtubule regulation. BSc5367 can be used in studies related to amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD), and several types of radiotherapy-resistant cancers.
Targets&IC50
NEK1: 11.5 nM
In vitro
BSc5367 is a potent Nek1 inhibitor with an IC50 of 11.5 nM[1].
AliasBSc 5367
Chemical Properties
Molecular Weight329.35
FormulaC20H15N3O2
Cas No.3029584-84-4
SmilesO=C(OC)C1=CC=CC(=C1)C2=CN=C3NC=C(C=4C=NC=CC4)C3=C2
Relative Density.no data available
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice.
Solubility Information
DMSO: 8.00 mg/mL (24.29 mM), Sonication is recommended.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.0363 mL15.1814 mL30.3628 mL151.8142 mL
5 mM0.6073 mL3.0363 mL6.0726 mL30.3628 mL
10 mM0.3036 mL1.5181 mL3.0363 mL15.1814 mL
20 mM0.1518 mL0.7591 mL1.5181 mL7.5907 mL

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