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BSc5367 is a potent inhibitor of the structural domain of Nek1 kinase with an IC50=11.5 nM. Nek1 is a NIMA-associated protein kinase tightly linked to cell cycle regulation, DNA repair, and microtubule regulation. BSc5367 can be used in studies related to amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD), and several types of radiotherapy-resistant cancers.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $98 | In Stock | |
5 mg | $178 | In Stock | |
10 mg | $283 | In Stock | |
25 mg | $595 | In Stock | |
50 mg | $923 | In Stock | |
100 mg | $1,438 | In Stock | |
1 mL x 10 mM (in DMSO) | $195 | In Stock |
Description | BSc5367 is a potent inhibitor of the structural domain of Nek1 kinase with an IC50=11.5 nM. Nek1 is a NIMA-associated protein kinase tightly linked to cell cycle regulation, DNA repair, and microtubule regulation. BSc5367 can be used in studies related to amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD), and several types of radiotherapy-resistant cancers. |
Targets&IC50 | NEK1: 11.5 nM |
In vitro | BSc5367 is a potent Nek1 inhibitor with an IC50 of 11.5 nM[1]. |
Alias | BSc 5367 |
Molecular Weight | 329.35 |
Formula | C20H15N3O2 |
Cas No. | 3029584-84-4 |
Smiles | O=C(OC)C1=CC=CC(=C1)C2=CN=C3NC=C(C=4C=NC=CC4)C3=C2 |
Relative Density. | no data available |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||
Solubility Information | DMSO: 8.00 mg/mL (24.29 mM), Sonication is recommended. | |||||||||||||||||||||||||
Solution Preparation Table | ||||||||||||||||||||||||||
DMSO
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