Powder: -20°C for 3 years | In solvent: -80°C for 1 year
BSc5367 is a potent inhibitor for the Nek1 kinase domain with an IC50 value of 11.5 nM. Nek1 is a NIMA-related protein kinase that crucially involved in cell cycle regulation, DNA repair and microtubule regulation. The Nek1 dysfunctions play key roles in amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD) and several types of radiotherapy resistant cancer. BSc5367 provides a useful tool to better understand the aforementioned diseases[1].
Pack Size | Availability | Price/USD | Quantity |
---|---|---|---|
25 mg | 10-14 weeks | $ 676.00 | |
50 mg | 10-14 weeks | $ 879.00 | |
100 mg | 10-14 weeks | $ 1,360.00 |
Description | BSc5367 is a potent inhibitor for the Nek1 kinase domain with an IC50 value of 11.5 nM. Nek1 is a NIMA-related protein kinase that crucially involved in cell cycle regulation, DNA repair and microtubule regulation. The Nek1 dysfunctions play key roles in amyotrophic lateral sclerosis (ALS), polycystic kidney disease (PKD) and several types of radiotherapy resistant cancer. BSc5367 provides a useful tool to better understand the aforementioned diseases[1]. |
Molecular Weight | 329.35 |
Formula | C20H15N3O2 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
You can also refer to dose conversion for different animals. More
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