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Ombuoside

Name: Ombuoside
Brand: TargetMol
SKU: TN2011
Price: 146 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. TN2011Cas No. 20188-85-6

Alias Ombuin-3beta-rutinoside

Ombuoside (Ombuin-3beta-rutinoside) has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.

Ombuoside

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Purity: 99.80%

Catalog No. TN2011Alias Ombuin-3beta-rutinosideCas No. 20188-85-6

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$38	In Stock	In Stock
5 mg	$98	In Stock	In Stock
10 mg	$146	In Stock	In Stock
25 mg	Preferential	In Stock	In Stock
50 mg	Preferential	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$113	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:99.80%

Resource Download

COA HPLC HNMR

Product Introduction

Bioactivity

Description	Ombuoside (Ombuin-3beta-rutinoside) has antifungal activity. Ombuoside shows significant antioxidant activity in the DPPH, and TEAC, reducing power assays.Ombuoside is a glycoside ombuoside isolated from Gynostemma pentaphyllum.
In vitro	Ombuoside and the synthetic derivatives octa-acetylOmbuoside, ombuine and retusine were tested for antimicrobial activity against several strains of Gram-positive and Gram-negative bacteria and the yeast Candida albicans, using the agar diffusion method. The flavonol glycoside Ombuoside and the respective aglycone ombuine, both exhibited moderated activity against Corynebacterium diphtheria, Staphylococcus aureus, Escherichia coli and Candida albicans. To a lesser degree, octaacetylOmbuoside and retusine showed activity against the Gram-positive bacteria C. diphtheria and S. aureus, but proved to be inactive against Gram-negative bacteria and Candida albicans[1]
Synonyms	Ombuin-3beta-rutinoside

Chemical Properties

Molecular Weight	638.57
Formula	C₂₉H₃₄O₁₆
Cas No.	20188-85-6
Smiles	COc1cc(O)c2c(c1)oc(-c1ccc(OC)c(O)c1)c(O[C@@H]1O[C@H](CO[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@@H](O)[C@H](O)[C@H]1O)c2=O
Relative Density.	1.66 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 65 mg/mL (101.79 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+90% Saline: 1.67 mg/mL (2.62 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5660 mL	7.8300 mL	15.6600 mL	78.3000 mL
5 mM	0.3132 mL	1.5660 mL	3.1320 mL	15.6600 mL
10 mM	0.1566 mL	0.7830 mL	1.5660 mL	7.8300 mL
20 mM	0.0783 mL	0.3915 mL	0.7830 mL	3.9150 mL
50 mM	0.0313 mL	0.1566 mL	0.3132 mL	1.5660 mL
100 mM	0.0157 mL	0.0783 mL	0.1566 mL	0.7830 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc