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Carbazeran

Name: Carbazeran
Brand: TargetMol
SKU: T21457
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T21457Cas No. 70724-25-3

Alias UK-31557, UK31557, UK-31,557, UK31,557, UK 31557, UK 31,557

Carbazeran (UK-31,557) is an inhibitor of PDE2 and PDE3 and can be used for studies about metabolic diseases. Carbazeran shows inotropic and chronotropic effects in vivo(EC50 = 100 μM).

Carbazeran

🥰Excellent

Purity: 99.3%

Catalog No. T21457Alias UK-31557, UK31557, UK-31,557, UK31,557, UK 31557, UK 31,557Cas No. 70724-25-3

Carbazeran (UK-31,557) is an inhibitor of PDE2 and PDE3 and can be used for studies about metabolic diseases. Carbazeran shows inotropic and chronotropic effects in vivo(EC50 = 100 μM).

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$37	In Stock	In Stock
5 mg	$59	In Stock	In Stock
10 mg	$93	In Stock	In Stock
25 mg	$188	In Stock	In Stock
50 mg	$285	In Stock	In Stock
100 mg	$428	-	In Stock
200 mg	$661	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.3%

Resource Download

COA HNMR LCMS

Product Introduction

Bioactivity

Description	Carbazeran (UK-31,557) is an inhibitor of PDE2 and PDE3 and can be used for studies about metabolic diseases. Carbazeran shows inotropic and chronotropic effects in vivo(EC50 = 100 μM).
Synonyms	UK-31557, UK31557, UK-31,557, UK31,557, UK 31557, UK 31,557

Chemical Properties

Molecular Weight	360.41
Formula	C₁₈H₂₄N₄O₄
Cas No.	70724-25-3
Smiles	CCNC(=O)OC1CCN(CC1)c1nncc2cc(OC)c(OC)cc12
Relative Density.	1.27g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (152.6 mM), Sonication is recommended.

H2O: Insoluble

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.7746 mL	13.8731 mL	27.7462 mL	138.7309 mL
5 mM	0.5549 mL	2.7746 mL	5.5492 mL	27.7462 mL
10 mM	0.2775 mL	1.3873 mL	2.7746 mL	13.8731 mL
20 mM	0.1387 mL	0.6937 mL	1.3873 mL	6.9365 mL
50 mM	0.0555 mL	0.2775 mL	0.5549 mL	2.7746 mL
100 mM	0.0277 mL	0.1387 mL	0.2775 mL	1.3873 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc