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Nateglinide

🥰Excellent
Catalog No. T1674Cas No. 105816-04-4
Alias Senaglinide, A4166

Nateglinide (Senaglinide) is an oral hypoglycemic agent and amino acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Nateglinide has been linked to rare instances of clinically apparent acute liver injury.

Nateglinide
Other Forms of Nateglinide:
Nateglinide D5T121781227666-13-8
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Nateglinide

🥰Excellent
Purity: 99.94%
Catalog No. T1674Alias Senaglinide, A4166Cas No. 105816-04-4
Nateglinide (Senaglinide) is an oral hypoglycemic agent and amino acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Nateglinide has been linked to rare instances of clinically apparent acute liver injury.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
25 mg$50In StockIn Stock
50 mg$89In StockIn Stock
100 mg$148In StockIn Stock
200 mg$215In StockIn Stock
1 mL x 10 mM (in DMSO)$35In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.94%
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Product Introduction

Bioactivity
Description
Nateglinide (Senaglinide) is an oral hypoglycemic agent and amino acid derivative that stimulates insulin secretion from the pancreas and is used in the therapy of type 2 diabetes. Nateglinide has been linked to rare instances of clinically apparent acute liver injury.
SynonymsSenaglinide, A4166
Chemical Properties
Molecular Weight317.42
FormulaC19H27NO3
Cas No.105816-04-4
SmilesC(N[C@H](CC1=CC=CC=C1)C(O)=O)(=O)[C@H]2CC[C@H](C(C)C)CC2
Relative Density.1.104 g/cm3 (Predicted)
Storage & Solubility Information
StoragePowder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 60 mg/mL (189.02 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (6.3 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM3.1504 mL15.7520 mL31.5040 mL157.5200 mL
5 mM0.6301 mL3.1504 mL6.3008 mL31.5040 mL
10 mM0.3150 mL1.5752 mL3.1504 mL15.7520 mL
20 mM0.1575 mL0.7876 mL1.5752 mL7.8760 mL
50 mM0.0630 mL0.3150 mL0.6301 mL3.1504 mL
100 mM0.0315 mL0.1575 mL0.3150 mL1.5752 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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μL
2 Enter the in vivo formulation:
% DMSO
%
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% Saline/PBS/ddH2O

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Keywords

β-cellshort-actingPPARγPotassiumChannelPotassium ChannelNateglinideKcsAinsulinInhibitorinhibitglucoseDPPDipeptidyl PeptidasediabetesA-4166A 4166
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