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(S)-DI-87((S)-TRE-515) is an isomer of DI-87.DI-87 is a novel and orally available dCK (deoxycytidine kinase) inhibitor with good in vitro activity and low protein binding.DI-87 binds to dCK and prevents the phosphorylation of deoxycytidine by dCK, resulting in a reduction in dNTP production and cell cycle arrest ( especially in S phase). When combined with thymidine, DI-87 significantly inhibits tumor growth.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
1 mg | $195 | In Stock | |
5 mg | $483 | In Stock | |
10 mg | $692 | In Stock | |
25 mg | $1,080 | In Stock | |
50 mg | $1,490 | In Stock | |
100 mg | $1,970 | In Stock | |
200 mg | $2,690 | In Stock |
Description | (S)-DI-87((S)-TRE-515) is an isomer of DI-87.DI-87 is a novel and orally available dCK (deoxycytidine kinase) inhibitor with good in vitro activity and low protein binding.DI-87 binds to dCK and prevents the phosphorylation of deoxycytidine by dCK, resulting in a reduction in dNTP production and cell cycle arrest ( especially in S phase). When combined with thymidine, DI-87 significantly inhibits tumor growth. |
Alias | (S)-TRE-515, (S)-DI87 |
Molecular Weight | 502.65 |
Formula | C23H30N6O3S2 |
Cas No. | 2107280-58-8 |
Smiles | [C@H](SC=1N=C(N)C=C(N)N1)(C)C=2N=C(SC2C)C3=CC(OCCN4CCOCC4)=C(OC)C=C3 |
Relative Density. | no data available |
Storage | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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