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Tavaborole

Name: Tavaborole
Brand: TargetMol
SKU: T3349
Price: 42 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T3349Cas No. 174671-46-6

Alias Kerydin, AN-2690

Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast.

Tavaborole

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Purity: 99.94%

Catalog No. T3349Alias Kerydin, AN-2690Cas No. 174671-46-6

Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast.

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$42	In Stock	In Stock
25 mg	$54	In Stock	In Stock
50 mg	$58	In Stock	In Stock
100 mg	$66	In Stock	In Stock
200 mg	$83	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$46	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Purity:99.94%

Appearance:Solid

Color:White

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COA HPLC HNMR

Product Introduction

Bioactivity

Description	Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast.
In vitro	AN-2690 demonstrates a significant enhancement in efficacy, exhibiting an 8-fold increase in activity against both C. neoformans and A. fumigatus. It effectively inhibits cells expressing GlLeuRS-D444A, yet shows no inhibitory effect on cells expressing GlLeuRS or GlLeuRS-D444E.
Synonyms	Kerydin, AN-2690

Chemical Properties

Molecular Weight	151.93
Formula	C₇H₆BFO₂
Cas No.	174671-46-6
Smiles	OB1C=2C(CO1)=CC(F)=CC2
Relative Density.	1.28 g/cm3 (Predicted)

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 250 mg/mL (1645.49 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (13.16 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	6.5820 mL	32.9099 mL	65.8198 mL	329.0989 mL
5 mM	1.3164 mL	6.5820 mL	13.1640 mL	65.8198 mL
10 mM	0.6582 mL	3.2910 mL	6.5820 mL	32.9099 mL
20 mM	0.3291 mL	1.6455 mL	3.2910 mL	16.4549 mL
50 mM	0.1316 mL	0.6582 mL	1.3164 mL	6.5820 mL
100 mM	0.0658 mL	0.3291 mL	0.6582 mL	3.2910 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc