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Tavaborole

🥰Excellent
Catalog No. T3349Cas No. 174671-46-6
Alias Kerydin, AN-2690

Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast.

Tavaborole

Tavaborole

🥰Excellent
Purity: 99.94%
Catalog No. T3349Alias Kerydin, AN-2690Cas No. 174671-46-6
Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast.
Pack SizePriceUSA WarehouseGlobal WarehouseQuantity
10 mg$42In StockIn Stock
25 mg$54In StockIn Stock
50 mg$58In StockIn Stock
100 mg$66In StockIn Stock
200 mg$83In StockIn Stock
1 mL x 10 mM (in DMSO)$46In StockIn Stock
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Purity:99.94%
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COA HNMR HPLC

Product Introduction

Bioactivity
Description
Tavaborole (Kerydin) is a boron-containing small molecule antifungal agent with broad-spectrum activity against filamentous fungi, including both mold and yeast.
In vitro
AN-2690 demonstrates a significant enhancement in efficacy, exhibiting an 8-fold increase in activity against both C. neoformans and A. fumigatus. It effectively inhibits cells expressing GlLeuRS-D444A, yet shows no inhibitory effect on cells expressing GlLeuRS or GlLeuRS-D444E.
SynonymsKerydin, AN-2690
Chemical Properties
Molecular Weight151.93
FormulaC7H6BFO2
Cas No.174671-46-6
SmilesOB1C=2C(CO1)=CC(F)=CC2
Relative Density.1.28 g/cm3 (Predicted)
ColorWhite
AppearanceSolid
Storage & Solubility Information
Storagestore at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
Solubility Information
DMSO: 50 mg/mL (329.1 mM), Sonication is recommended.
In Vivo Formulation
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (13.16 mM), Sonication is recommended.
Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.
Solution Preparation Table
DMSO
1mg5mg10mg50mg
1 mM6.5820 mL32.9099 mL65.8198 mL329.0989 mL
5 mM1.3164 mL6.5820 mL13.1640 mL65.8198 mL
10 mM0.6582 mL3.2910 mL6.5820 mL32.9099 mL
20 mM0.3291 mL1.6455 mL3.2910 mL16.4549 mL
50 mM0.1316 mL0.6582 mL1.3164 mL6.5820 mL
100 mM0.0658 mL0.3291 mL0.6582 mL3.2910 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
TargetMol | Animal experimentsFor example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH2O. So your working solution concentration is 2 mg/mL。
Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSOTargetMol | reagent (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
Preparation method for in vivo formula: Take 50 μL DMSOTargetMol | reagent main solution, add 300 μLPEG300TargetMol | reagent mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH2OTargetMol | reagent mix well and clarify
For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.
1 Enter information below:
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2 Enter the in vivo formulation:
% DMSO
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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

Keywords

TavaboroleInhibitorinhibitFungalAntifungalAntibioticAN2690AN 2690
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