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ARS-1323

Name: ARS-1323
Brand: TargetMol
SKU: T10375
Price: 34 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T10375Cas No. 1698024-73-5

ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor.

ARS-1323

🥰Excellent

Purity: 99.53%

Catalog No. T10375Cas No. 1698024-73-5

ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor.

Pack Size	Price	USA Warehouse	Global Warehouse
2 mg	$34	In Stock	In Stock
5 mg	$54	In Stock	In Stock
10 mg	$90	In Stock	In Stock
25 mg	$138	In Stock	In Stock
50 mg	$180	In Stock	In Stock
100 mg	$261	In Stock	In Stock
200 mg	$389	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$60	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.53%

Appearance:Solid

Color:White

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description

ARS-1323 is the racemate of ARS-1620 and a mutant K-ras G12C inhibitor.

Chemical Properties

Molecular Weight	430.84
Formula	C₂₁H₁₇ClF₂N₄O₂
Cas No.	1698024-73-5
Smiles	FC=1C2=C(C(=NC=N2)N3CCN(C(C=C)=O)CC3)C=C(Cl)C1C4=C(F)C=CC=C4O
Relative Density.	1.434 g/cm3 (Predicted)

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 125 mg/mL (290.13 mM), Sonication is recommended.

In Vivo Formulation

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 4 mg/mL (9.28 mM), Sonication is recommended.

Please add the solvents sequentially, clarifying the solution as much as possible before adding the next one. Dissolve by heating and/or sonication if necessary. Working solution is recommended to be prepared and used immediately. The formulation provided above is for reference purposes only. In vivo formulations may vary and should be modified based on specific experimental conditions.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.3210 mL	11.6052 mL	23.2105 mL	116.0524 mL
5 mM	0.4642 mL	2.3210 mL	4.6421 mL	23.2105 mL
10 mM	0.2321 mL	1.1605 mL	2.3210 mL	11.6052 mL
20 mM	0.1161 mL	0.5803 mL	1.1605 mL	5.8026 mL
50 mM	0.0464 mL	0.2321 mL	0.4642 mL	2.3210 mL
100 mM	0.0232 mL	0.1161 mL	0.2321 mL	1.1605 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc