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AnnH31

Name: AnnH31
Brand: TargetMol
SKU: T26632
Price: 90 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T26632Cas No. 241809-12-1

AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm the involvement of DYRK1A in cellular phosphorylation.

AnnH31

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Purity: 99.88%

Catalog No. T26632Cas No. 241809-12-1

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$90	-	In Stock
5 mg	$222	-	In Stock
10 mg	$309	-	In Stock
25 mg	$487	-	In Stock
50 mg	$643	-	In Stock
100 mg	$826	-	In Stock
200 mg	$1,100	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.88%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	AnnH31 is a potent Dyrk1A inhibitor with an IC50 value of 81 nM.AnnH31 inhibits MAO-A with an IC50 of 3.2 μM.AnnH31 can be used as a probe to confirm the involvement of DYRK1A in cellular phosphorylation.
Targets&IC50	Dyrk1A:81 nM, MAO-A:3.2 μM

Chemical Properties

Molecular Weight	251.28
Formula	C₁₅H₁₃N₃O
Cas No.	241809-12-1
Smiles	C(C#N)N1C=2C(C=3C1=C(C)N=CC3)=CC=C(OC)C2
Relative Density.	1.22 g/cm3 (Predicted)
Color	Yellow
Appearance	Solid

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 50 mg/mL (198.98 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.9796 mL	19.8981 mL	39.7962 mL	198.9812 mL
5 mM	0.7959 mL	3.9796 mL	7.9592 mL	39.7962 mL
10 mM	0.3980 mL	1.9898 mL	3.9796 mL	19.8981 mL
20 mM	0.1990 mL	0.9949 mL	1.9898 mL	9.9491 mL
50 mM	0.0796 mL	0.3980 mL	0.7959 mL	3.9796 mL
100 mM	0.0398 mL	0.1990 mL	0.3980 mL	1.9898 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc