Shopping Cart
- Remove All
Your shopping cart is currently empty
Mal-Exatecan
😃Good
Catalog No. T205546Cas No. 3028213-52-4
Mal-Exatecan, a derivative of Exatecan modified with maleimide (Mal), functions as an inhibitor of DNA topoisomerase I (topoisomeraseI).
Mal-Exatecan
😃Good
Catalog No. T205546Cas No. 3028213-52-4
Mal-Exatecan, a derivative of Exatecan modified with maleimide (Mal), functions as an inhibitor of DNA topoisomerase I (topoisomeraseI).
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 10 mg | Inquiry | 10-14 weeks | |
| 50 mg | Inquiry | 10-14 weeks |
Bulk & Custom
Questions
View MoreInhibitors Related to "Mal-Exatecan"
Levofloxacin
Cited
Tavanic, Levaquin, Fluoroquinolone, Cravit, (-)-Ofloxacin
T6567100986-85-4
Levofloxacin ((-)-Ofloxacin) is a synthetic fluoroquinolone antibiotic that inhibits the superhelical activity of bacterial DNA rotamase and prevents DNA replication. Levofloxacin is a broad-spectrum antibiotic used for the treatment of a wide range of bacterial infections.
- $48
Size
QTY
CitedLevofloxacin hydrochloride
T8747177325-13-2
Levofloxacin is a broad-spectrum, third-generation fluoroquinolone antibiotic and optically active L-isomer of ofloxacin with antibacterial activity. Levofloxacin diffuses through the bacterial cell wall and acts by inhibiting DNA gyrase (bacterial topoisomerase II), an enzyme required for DNA replication, RNA transcription, and repair of bacterial DNA. Inhibition of DNA gyrase activity leads to blockage of bacterial cell growth.
- $37
Size
QTY
Ciprofloxacin monohydrochloride Cited
Ciprofloxacin hydrochloride, Ciprofloxacin HCl, Bay-09867 (hydrochloride)
T025093107-08-5
Ciprofloxacin monohydrochloride (Bay-09867 hydrochloride) is a broad-spectrum antimicrobial carboxyfluoroquinoline.
- $41
Size
QTY
CitedNorfloxacin Cited
MK-0366
T130670458-96-7
Norfloxacin (MK-0366)(Norxacin) is a broad-spectrum antibiotic that is active against both Gram-positive and Gram-negative bacteria.
- $41
Size
QTY
CitedPaclitaxel
Cited
Taxol, NSC 125973
T096833069-62-4
Paclitaxel (Taxol) is a natural product and a microtubule polymer stabilizer. Paclitaxel has anti-tumor activity and causes cell death by inducing mitotic arrest, apoptosis, and cell autophagy.
- $34
Size
QTY
CitedDexamethasone Cited
Prednisolone F, NSC 34521, MK 125, Hexadecadrol
T107650-02-2
Dexamethasone (Hexadecadrol) is a glucocorticoid receptor agonist and IL receptor modulator with anti-inflammatory and immunosuppressive properties that induces autophagy and inhibits LPS-induced inflammatory responses in macrophages.
ADC CytotoxinAntibacterialAntibioticAutophagyComplement SystemGlucocorticoid ReceptorIL ReceptorMitophagySARS-CoV
- $29
Size
QTY
CitedEIDD-1931 Cited
Beta-d-N4-hydroxycytidine
T84983258-02-4
EIDD-1931 (Beta-d-N4-hydroxycytidine) is a ribonucleoside analog with antiviral activity that inhibits the replication of severe acute respiratory syndrome coronavirus [SARS-CoV] in Vero 76 cells, Middle East respiratory syndrome coronavirus [MERS-CoV] in Calu-3 2B4 cells, and SARS-CoV-2 in Vero cells (IC50s = 0.1, 0.15, and 0.3 μM, respectively).
- $33
Size
QTY
CitedMethotrexate disodium
T80037413-34-5
Methotrexate disodium is an tetrahydrofolate dehydrogenase inhibitor
- $34
Size
QTY
Etoposide Cited
VP-16-213, VP-16
T013233419-42-0
Etoposide (VP-16-213) is a topoisomerase II inhibitor that inhibits DNA synthesis by forming a complex with topoisomerase II and DNA (IC50=60.3 μM). Etoposide has antitumor activity and induces apoptosis and autophagy.
- $33
Size
QTY
CitedBerberine chloride
Natural Yellow 18, Berberine hydrochloride, Benzodioxide
T0461633-65-8
Berberine chloride (Natural Yellow 18) is an alkaloid from Hydrastis canadensis L., Berberidaceae and also found in many other plants. It is relatively toxic to parenterally but has been used orally for various fungal and parasitic infections and an anti-diarrheal.
- $29
Size
QTY
Ofloxacin Cited
Tarivid, Oxaldin, Hoe-280, Floxin, DL8280
T090282419-36-1
Ofloxacin (Oxaldin) is a fluoroquinolone antibacterial antibiotic. Ofloxacin binds to and inhibits bacterial topoisomerase II (DNA gyrase) and topoisomerase IV, enzymes involved in DNA replication and repair, resulting in cell death in sensitive bacterial species.
- $30
Size
QTY
Cited1,4-Naphthoquinone Cited
α-Naphthoquinone, P-Naphthoquinone, para-naphthoquinone, Naphthalene-1,4-Dione
T7048130-15-4
1,4-Naphthoquinone (P-Naphthoquinone) was used as a potential inhibitor of monoamine oxidase and DNA topoisomerase activities[2]. It was also used to inhibit the acetyltransferase activity[1].
- $31
Size
QTY
CitedContact us for more batch information
Resource Download
Product Introduction
Bioactivity
Chemical Properties
| Description | Mal-Exatecan, a derivative of Exatecan modified with maleimide (Mal), functions as an inhibitor of DNA topoisomerase I (topoisomeraseI). |
| Molecular Weight | 628.647 |
| Formula | C34H33FN4O7 |
| Cas No. | 3028213-52-4 |
Storage & Solubility Information
| Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
Sci Citations
Calculator
In Vivo Formulation Calculator (Clear solution)
Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:
For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . A total of 10 animals were administered, and the formula you used is 5% 
DMSO+30% PEG300+5% Tween 80+60% ddH2O. So your working solution concentration is 2 mg/mL。Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO (mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.
(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.Preparation method for in vivo formula: Take 50 μL DMSO main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarify
main solution, add 300 μLPEG300 mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLddH2O mix well and clarifyFor Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.
Dose Conversion
You can also refer to dose conversion for different animals. More Dose Conversion
Tech Support
Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
Preview
Related Tags: buy Mal-Exatecan | purchase Mal-Exatecan | Mal-Exatecan cost | order Mal-Exatecan | Mal-Exatecan chemical structure | Mal-Exatecan formula | Mal-Exatecan molecular weight
- TOP
Feedback
Hello! How can I help you today? 
Copyright © 2015-2025 TargetMol Chemicals Inc. All Rights Reserved.