Shopping Cart

Remove All
Your shopping cart is currently empty

Dabigatran etexilate

Name: Dabigatran etexilate
Brand: TargetMol
SKU: T0389
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

🥰Excellent

Catalog No. T0389Cas No. 211915-06-9

Alias BIBR 1048

Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor that binds to thrombin, blocking its thrombogenic activity and preventing thrombus formation.

Dabigatran etexilate

🥰Excellent

Purity: 99.12%

Catalog No. T0389Alias BIBR 1048Cas No. 211915-06-9

Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor that binds to thrombin, blocking its thrombogenic activity and preventing thrombus formation.

Pack Size	Price	Availability
2 mg	$30	In Stock
5 mg	$48	In Stock
10 mg	$68	In Stock
50 mg	$89	In Stock
100 mg	$120	In Stock
200 mg	$175	In Stock
1 mL x 10 mM (in DMSO)	$73	In Stock

Add to Cart

Add to Quotation

Bulk & Custom

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

Select Batch

Purity:99.12%

Resource Download

COA HNMR HPLC

Product Introduction

Bioactivity

Description	Dabigatran etexilate (BIBR 1048) is a thrombin inhibitor that binds to thrombin, blocking its thrombogenic activity and preventing thrombus formation.
Targets&IC50	DTI:4.5 nM (Ki)
In vitro	Dabigatran has a concentration-dependent anticoagulant effect in various animals.Dabigatran reversibly inhibits human thrombin (Ki: 4.5 nM) and thrombin-induced platelet aggregation (IC50= 10 nM).
In vivo	Dabigatran has a concentration-dependent anticoagulant effect in various animals.Dabigatran reversibly inhibits human thrombin (Ki: 4.5 nM) and thrombin-induced platelet aggregation (IC50= 10 nM).
Synonyms	BIBR 1048

Chemical Properties

Molecular Weight	627.73
Formula	C₃₄H₄₁N₇O₅
Cas No.	211915-06-9
Smiles	CCCCCCOC(=O)N\N=C\c1ccc(NCc2nc3cc(ccc3n2C)C(=O)N(CCC(=O)OCC)c2ccccn2)cc1
Relative Density.	1.24 g/cm3
Color	White
Appearance	Solid

Storage & Solubility Information

Storage

store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 116 mg/mL (184.79 mM), Sonication is recommended.

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: 10 mg/mL (15.93 mM), Sonication is recommended.

Solution Preparation Table

Ethanol/DMSO

	1mg	5mg	10mg	50mg
1 mM	1.5930 mL	7.9652 mL	15.9304 mL	79.6521 mL
5 mM	0.3186 mL	1.5930 mL	3.1861 mL	15.9304 mL
10 mM	0.1593 mL	0.7965 mL	1.5930 mL	7.9652 mL

DMSO

	1mg	5mg	10mg	50mg
20 mM	0.0797 mL	0.3983 mL	0.7965 mL	3.9826 mL
50 mM	0.0319 mL	0.1593 mL	0.3186 mL	1.5930 mL
100 mM	0.0159 mL	0.0797 mL	0.1593 mL	0.7965 mL

Calculator

Molarity Calculator
Dilution Calculator
Reconstitution Calculator
Molecular Weight Calculator

In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Sci Citations

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc