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  • Inhibitors & Agonists
    7268
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    TargetMol | Inhibitors_Agonists
Denifanstat
TVB-2640, TVB2640, FASN-IN-2
T152711399177-37-7
Denifanstat (FASN-IN-2) is a fatty acid synthase (FASN) inhibitor (IC50=0.052 μM, EC50=0.072 μM) with selective and oral activity. Denifanstat has been used in studies of steatohepatitis.
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G-418 disulfate
Geneticin sulfate, Geneticin, G418 Sulfate, Antibiotic G-418 sulfate
T6512108321-42-2
G-418 disulfate (Geneticin sulfate) is an aminoglycoside antibiotic that selectively inhibits eukaryotic protein synthesis by blocking peptide chain elongation.
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Neomycin sulfate
Framycin sulfate
T09501405-10-3
Neomycin sulfate (Framycin sulfate) is a broad-spectrum aminoglycoside antibiotic that blocks the synthesis of bacterial proteins in order to exert antimicrobial activity. Neomycin sulfate is commonly used to screen prokaryotic and eukaryotic cells for Neo resistance genes.
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7-10 days
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Trimethoprim
NSC-106568, NIH 204, BW 56-72
T1153738-70-5
Trimethoprim (NSC-106568) is a Dihydrofolate Reductase Inhibitor Antibacterial. The mechanism of action of trimethoprim is as a Dihydrofolate Reductase Inhibitor, and Cytochrome P450 2C8 Inhibitor, and Organic Cation Transporter 2 Inhibitor.
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Tetracaine hydrochloride
Tetracaine HCl, Amethocalne HCl, Amethocaine hydrochloride
T1198136-47-0
Tetracaine hydrochloride (Amethocalne HCl) (Pontocaine), a potent local anaesthetic, is a channel function allosteric inhibitor. It is primarily used as an antipruritic and topically in ophthalmology, and it has been used for surface and spinal anesthesia.
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N-Succinimidyl-S-acetylthioacetate
SATA
T1625176931-93-6
N-Succinimidyl-S-acetylthioacetate (SATA) is a protein modification agent that introduces thiol-groups into protein molecules and adds sulfhydryl groups in a protected form to proteins and other amine-containing molecules for later reaction with sulfhydryl reactive crosslinkers such as Sulfo-SMCC, Sulfo-MBS, etc.
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PTP inhibitor 1
PTP Inhibitor II
T75412632-13-5
PTP inhibitor 1 is an inhibitor of cell-permeable protein tyrosine phosphatase (PTP) that covalently binds the catalytic domain of the Src homology region 2 domain-containing phosphatase (SHP-1(ΔSH2)),with Ki of128 μM.
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Potassium acetate
Potassium ethanoate, Diuretic salt
T8129127-08-2
Potassium acetate (Diuretic salt) with antibacterial and antifungal properties.
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HA-100
T764884468-24-6
HA-100 is an inhibitor of protein kinase
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SD-169
SD 169
T76611670-87-7
SD-169 (SD 169) is a selective and ATP competitive the MAP kinases p38α and p38β inhibitor.
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XMD8-92
T18431234480-50-2
XMD8-92 is an effective and specific BMK1 ERK5 inhibitor (Kd: 80 nM).
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N1-Methylpseudouridine
1-Methylpseudouridine
T1945913860-38-3
N1-Methylpseudouridine (1-Methylpseudouridine) is a methylpseudouridine and enhances translation through eIF2α-dependent and independent mechanisms by increasing ribosome density in mRNA.
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pf-6274484
PF 6274484
T223961035638-91-5
PF-6274484, a high affinity, irreversible covalent inhibitor of EGFR kinase with Ki of 0.14 nM, inhibits the autophosphorylation of wild-type EGFR in A549 cells and EGFRL858R T790M in H1975 cells with IC50 of 5.8 nM and 6.6 nM, respectively.
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Amikacin hydrate
BAY 41-6551 hydrate
T63831257517-67-1
Amikacin hydrate (BAY 41-6551 hydrate) is an aminoglycoside antibiotic with bacteriostatic activity used in studies of drug-resistant Mycobacterium tuberculosis infections and Gram-negative bacterial infections, and is commonly used in the clinic for urinary tract infections caused by E. coli.
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7-10 days
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LLY-507
LLY507, LLY 507
T68791793053-37-8
LLY-507 is an effective, cell-active, and specific inhibitor of protein-lysine Methyltransferase SMYD2.
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Lonicerin
TN187725694-72-8
Lonicerin has antioxidant, anti-arthritic and antifungal activities, it can result in a combination therapy for the treatment of fungal arthritis due to C. albicans infection.
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L-Alanyl-L-glutamine
Ala-Gln
T559339537-23-0
L-Alanyl-L-glutamine (Ala-Gln), a dipeptide composed of alanine and Gln, is an alternative supplement to L-glutamine in the production of biopharmaceuticals with better solubility and stability than glutamine (Gln).
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Protein kinase inhibitor H-7 dihydrochloride
H-7 dihydrochloride
T22831108930-17-2
Protein kinase inhibitor H-7 dihydrochloride(H-7 dihydrochloride) is a potent protein kinase C (PKC) inhibitor. Protein kinase inhibitor H-7 dihydrochloride (100 μM) significantly inhibits TPA (skin tumor promoter, 12-O-tetradecanoylphorbol-13-acetate) and phospholipase C-induced ODC (ornithine decarboxylase) inhibited PMA-induced promiscuity cell lysis activity.
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7-10 days
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Protein kinase inhibitor H-7
5-(2-methylpiperazine-1-sulfonyl)isoquinoline, 1-(5-Isoquinolinylsulfonyl)-2-methylpiperazine
T6010984477-87-2
Protein kinase inhibitor H-7 (5-(2-methylpiperazine-1-sulfonyl)isoquinoline) is a potent inhibitor of protein kinase C (PKC) with a Ki of 6 μM. Protein kinase inhibitor H-7 is also a cyclic nucleotide dependent protein kinase inhibitor.
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Protein kinase G inhibitor-1
T67755354544-70-0
Protein kinase G inhibitor-1 is a potent Protein kinase G inhibitor, IC50= 0.9 uM.
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Protein kinase inhibitor 6
T9779348-45-8
Protein kinase inhibitor 6 (PKI 6) is a compound that acts as an inhibitor of protein kinases.
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Protein kinase G inhibitor-2
T9940612829-80-8
Protein kinase G inhibitor-2 exhibits antibacterial, antiviral, and antitumor activities.
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Protein Kinase C Peptide Substrate acetate
Protein Kinase C Peptide Substrate acetate(120253-69-2 free base)
TP1051L
Protein Kinase C Peptide Substrate acetate targets specific cell spacers ina manner that is dependent on second messengers and specific adaptor proteins in response to extracellular signals that activate g protein-coupled receptors, tyrosine Kinase recept
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Protein Kinase C 19-31 acetate
Protein Kinase C 19-31 acetate(121545-65-1 free base), PKC (19-31) acetate
TP1053L
Protein Kinase C 19-31 acetate, a peptide inhibitor of protein kinase C (PKC), derived from the pseudo-substrate regulatory domain of PKCa (residues 19-31) with a serine at position 25 replacing the wild-type alanine, is used as protein kinase C substrate
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