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Anti-MRC1 Antibody (6M291)

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Catalog No. TMAC-02449

Anti-MRC1 Antibody (6M291) is a Rabbit antibody targeting MRC1. Anti-MRC1 Antibody (6M291) can be used in WB,ICC/IF.

Anti-MRC1 Antibody (6M291)

Anti-MRC1 Antibody (6M291)

😃Good
Catalog No. TMAC-02449
Anti-MRC1 Antibody (6M291) is a Rabbit antibody targeting MRC1. Anti-MRC1 Antibody (6M291) can be used in WB,ICC/IF.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-MRC1 Antibody (6M291) is a Rabbit antibody targeting MRC1. Anti-MRC1 Antibody (6M291) can be used in WB,ICC/IF.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:1000-5000; ICC/IF: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCD206, also known as macrophage mannose receptor type C (MMR or MRC1), is a type I membrane receptor protein. It is an phagocytic and endocytic receptor that can recognize carbohydrate ligands in target molecules. The extracellular portion of the protein includes eight C-type carbohydrate recognition domains (CRD) which are clustered together to achieve higher affinity binding to saccharides. CD206 is found on macrophages and on endothelial cells of the liver and is the only known example of a C-type lectin that contains multiple C-type CRDs. CD206 mediates the endocytosis of glycoproteins by macrophages and binds high-mannose structures on the surface of potentially pathogenic viruses, fungi and bacteria enabling them to be neutralized by phagocytic engulfment. During inflammation, CD206 is crucial for rapid clearance of several mannose-bearing serum glycoproteins but does not regulate the initiation of inflammation. CD206 is primarily expressed in mature tissue macrophages and immature dendritic cells, as well as hepatic and lymphatic endothelial cells, retinal pigmental epithelium (RPE) and mesangial cells.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 166/140 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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