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Anti-KRT1 Antibody (8C677) (Synonyms: Type-II keratin Kb1, type II cytoskeletal 1, KRTA, KRT1, Keratin-1 (K1...)

Catalog No. TMAC-01073 Copy Product Info
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Anti-KRT1 Antibody (8C677) is a Rabbit antibody targeting KRT1. Anti-KRT1 Antibody (8C677) can be used in IHC,WB.

Anti-KRT1 Antibody (8C677)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01073
Synonyms Type-II keratin Kb1, type II cytoskeletal 1, KRTA, KRT1, Keratin-1 (K1), Keratin, type II cytoskeletal 1, Hair alpha protein, Cytokeratin-1 (CK-1), 67 kDa cytokeratin

Anti-KRT1 Antibody (8C677) is a Rabbit antibody targeting KRT1. Anti-KRT1 Antibody (8C677) can be used in IHC,WB.

Anti-KRT1 Antibody
(8C677)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-KRT1 Antibody (8C677) is a Rabbit antibody targeting KRT1. Anti-KRT1 Antibody (8C677) can be used in IHC,WB.
SynonymsType-II keratin Kb1, type II cytoskeletal 1, KRTA, KRT1, Keratin-1 (K1), Keratin, type II cytoskeletal 1, Hair alpha protein, Cytokeratin-1 (CK-1), 67 kDa cytokeratin
Ig Type
IgG
Clone
8C677
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of Cytokeratin 1 on different lysates using anti-Cytokeratin 1 antibody at 1/1,000 dilution. Positive control: Lane 1: 293T, Lane 2: Hela.
2. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Cytokeratin 1 antibody. Counter stained with hematoxylin.
verifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:1000; IHC: 1:100-500
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundCytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins constitute up to 85% of a mature keratinocytes in the vertebrate epidermis. Cytokeratins play a critical role in differentiation and tissue specialization, and they function to maintain the overall structural integrity of epithelial cells. The alpha-helical coiled-coil dimers associate laterally end-to-end to form 10-nm diameter filaments. Cytokeratins are useful markers of tissue differentiation, and they aid in the characterization of malignant tumors. Cytokeratin 1 is highly expressed in several malignancies including epithelioid hemangioendohtheliomas, angiosarcomas, schwannomas, epithelioid sarcomas and synodal sarcomas. The gene encoding human Cytokeratin 1 maps to chromosome 12q13.13. Mutations in the gene encoding human Cytokeratin 1 lead to abnormal filament associations and epidermolytic hyperkeratosis.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 72 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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