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Anti-CTLA-4 Antibody-Biotin (8I311) (Synonyms: IDDM12, GSE, GRD4, cytotoxic T-lymphocyte-associated protein 4...)
Catalog No. TMAY-01710B Copy Product Info
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Anti-CTLA-4 Antibody-Biotin (8I311) is a Biotin-conjugated Mouse antibody targeting CTLA-4. Anti-CTLA-4 Antibody-Biotin (8I311) can be used in ELISA.
Anti-CTLA-4 Antibody-Biotin (8I311)
Copy Product Info🥰Excellent
Catalog No. TMAY-01710B
Synonyms IDDM12, GSE, GRD4, cytotoxic T-lymphocyte-associated protein 4, CTLA-4, CELIAC3, CD152, CD, ALPS5
Anti-CTLA-4 Antibody-Biotin (8I311) is a Biotin-conjugated Mouse antibody targeting CTLA-4. Anti-CTLA-4 Antibody-Biotin (8I311) can be used in ELISA.
Anti-CTLA-4 Antibody-Biotin
(8I311)
(8I311)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 100 μg | $293 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-CTLA-4 Antibody-Biotin (8I311) is a Biotin-conjugated Mouse antibody targeting CTLA-4. Anti-CTLA-4 Antibody-Biotin (8I311) can be used in ELISA. |
| Synonyms | IDDM12, GSE, GRD4, cytotoxic T-lymphocyte-associated protein 4, CTLA-4, CELIAC3, CD152, CD, ALPS5 |
| Ig Type | Mouse IgG2b |
| Clone | 8I311 |
| Reactivity | Human |
| Specificity | Human CTLA-4 |
| Application | |
| Recommended Dose | ELISA: 0.1-1 μg/ml |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human CTLA-4 / CD152 (rh CTLA-4 / CD152; TMPY-04348; NP_005205.2; Met1-Phe162). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography and then biotinylated. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Cytotoxic T-lymphocyte protein 4, also known as CTLA4 and CD152, is a single-pass type I membrane protein and a member of the immunoglobulin superfamily. It is the second member of the CD28 receptor family. The ligands or counterreceptors for these two proteins are the B7 family members, CD80 (B7-1) and CD86 (B7-2). CTLA4 transmits an inhibitory signal to T cells, whereas CD28 transmits a stimulatory signal. Intracellular CTLA4 is also found in regulatory T cells and may play an important role in their functions. CD152 or cytotoxic T lymphocyte antigen-4 (CTLA-4) is an essential receptor involved in the negative regulation of T cell activation. Because of its profound inhibitory role, CD152 has been considered a sound susceptible candidate in autoimmunity and a persuasive target for cancer immunotherapy. In particular, recent evidence suggests that CD152 is also important in the homeostasis and function of a population of suppressive cells, termed regulatory T cells (Treg).Cancer ImmunotherapyCo-inhibitory Immune Checkpoint TargetsCTLA4 / CD152 Immune Checkpoint ProteinsImmune CheckpointImmune Checkpoint Detection: AntibodiesImmune Checkpoint Detection: ELISA AntibodiesImmune Checkpoint Detection: IP AntibodiesImmune Checkpoint Detection: WB AntibodiesImmune Checkpoint ProteinsImmune Checkpoint TargetsImmunotherapyTargeted Therapy |
| Conjucates | Biotin |
| Others Formats | Unconjugated |
| Antibody Types Available | 2 |
| Immunogen | Recombinant Protein: Human CTLA-4 / CD152 protein (TMPY-04348) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules, Cancer Drug Targets |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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