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Anti-WSTF Antibody (7C137) is a Rabbit antibody targeting WSTF. Anti-WSTF Antibody (7C137) can be used in WB,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $298 | 7-10 days | |
100 μL | $496 | 7-10 days |
Description | Anti-WSTF Antibody (7C137) is a Rabbit antibody targeting WSTF. Anti-WSTF Antibody (7C137) can be used in WB,FCM. |
Synonyms | WSTF, Williams-Beuren syndrome chromosomal region 9 protein, Williams-Beuren syndrome chromosomal region 10 protein, Williams syndrome transcription factor, Williams Beuren syndrome chromosome region 9 protein, WBSCR9, WBSCR10, WBSC-10, WBSC10, WBSC 10, WBRS-9, WBRS9, WBRS 9, WALP-2, WALP2, Tyrosine-protein kinase BAZ1B, transcription factor WSTF, hWALP-2, hWALP2, hWALP 2, Bromodomain adjacent to zinc finger domain protein 1B, BAZ1B_HUMAN, baz1b |
Ig Type | IgG |
Reactivity | Human,Mouse,Rat |
Verified Activity | 1. Western blot analysis of WSTF on SiHa cell lysates using anti-WSTF at 1/500 dilution. 2. Flow cytometric analysis of K562 cells with WSTF antibody at 1/50 dilution (Fuchsia) compared with an unlabelled control (cells without incubation with primary antibody; Yellow). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
Application | |
Recommended Dose | WB: 1:500-1000; FCM: 1:50-100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Atypical tyrosine-protein kinase that plays a central role in chromatin remodeling and acts as a transcription regulator. Involved in DNA damage response by phosphorylating 'Tyr-142' of histone H2AX (H2AXY142ph). H2AXY142ph plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Essential component of the WICH complex, a chromatin remodeling complex that mobilizes nucleosomes and reconfigures irregular chromatin to a regular nucleosomal array structure. The WICH complex regulates the transcription of various genes, has a role in RNA polymerase I and RNA polymerase III transcription, mediates the histone H2AX phosphorylation at 'Tyr-142', and is involved in the maintenance of chromatin structures during DNA replication processes. In the complex, it mediates the recruitment of the WICH complex to replication foci during DNA replication. |
Conjucates | Unconjugated |
Uniprot ID |
Molecular Weight | Theoretical: 171 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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