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Anti-GRIM19 Antibody (2M560)

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Catalog No. TMAC-01713

Anti-GRIM19 Antibody (2M560) is a Rabbit antibody targeting GRIM19. Anti-GRIM19 Antibody (2M560) can be used in WB,IHC,ICC.

Anti-GRIM19 Antibody (2M560)

Anti-GRIM19 Antibody (2M560)

😃Good
Catalog No. TMAC-01713
Anti-GRIM19 Antibody (2M560) is a Rabbit antibody targeting GRIM19. Anti-GRIM19 Antibody (2M560) can be used in WB,IHC,ICC.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-GRIM19 Antibody (2M560) is a Rabbit antibody targeting GRIM19. Anti-GRIM19 Antibody (2M560) can be used in WB,IHC,ICC.
Ig Type
IgG
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe GRIM family of proteins appear to be novel types of tumor suppressors. Grim19, which stands for gene associated with retinoic-interferon-induced mortality 19 protein, is also designated cell death-regulatory protein Grim-19 or NADH dehydrogenase ubiquinone 1 alpha subcomplex subunit 13. The Grim19 protein plays two roles within the cell. As a member of the interferon-beta and retinoic acid-induced pathway of cell death, Grim19 induces apoptosis. As part of the mitochondrial complex I, Grim19 is essential for its assembly and electron transfer activity. It transfers electrons to the respiratory chain from NADH and plays a role in the interferon/all-trans-retinoic acid (IFN/RA) cell death pathway. It localizes primarily to the mitochondrion, but may translocate to the nucleus upon IFN/RA treatment. Grim19 may also be useful as a biological marker or target for drug development.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: human GRIM19 aa 1-150
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 17 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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