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Anti-GRIM19 Antibody (2M560)
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Catalog No. TMAC-01713
Alias RGD1565358, NDUFA13, NDUAD_HUMAN, NADH-ubiquinone oxidoreductase B16.6 subunit, NADH ubiquinone oxidoreductase B16.6 subunit, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13, GRIM-19, Gene associated with retinoic interferon induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 protein, Gene associated with retinoic and IFN-induced mortality 19 protein, FLJ59191, FLJ58045, Complex I-B16.6, CI-B16.6, CGI39 protein, CGI-39, Cell death regulatory protein GRIM-19, Cell death regulatory protein, CDA016, B16.6, AU022060, 2700054G14Rik
Anti-GRIM19 Antibody (2M560) is a Rabbit antibody targeting GRIM19. Anti-GRIM19 Antibody (2M560) can be used in WB,IHC,ICC.
Anti-GRIM19 Antibody (2M560)
Anti-GRIM19 Antibody (2M560)
😃Good
Catalog No. TMAC-01713Alias RGD1565358, NDUFA13, NDUAD_HUMAN, NADH-ubiquinone oxidoreductase B16.6 subunit, NADH ubiquinone oxidoreductase B16.6 subunit, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13, GRIM-19, Gene associated with retinoic interferon induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 protein, Gene associated with retinoic and IFN-induced mortality 19 protein, FLJ59191, FLJ58045, Complex I-B16.6, CI-B16.6, CGI39 protein, CGI-39, Cell death regulatory protein GRIM-19, Cell death regulatory protein, CDA016, B16.6, AU022060, 2700054G14Rik
Anti-GRIM19 Antibody (2M560) is a Rabbit antibody targeting GRIM19. Anti-GRIM19 Antibody (2M560) can be used in WB,IHC,ICC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $298 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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| Description | Anti-GRIM19 Antibody (2M560) is a Rabbit antibody targeting GRIM19. Anti-GRIM19 Antibody (2M560) can be used in WB,IHC,ICC. |
| Synonyms | RGD1565358, NDUFA13, NDUAD_HUMAN, NADH-ubiquinone oxidoreductase B16.6 subunit, NADH ubiquinone oxidoreductase B16.6 subunit, NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 13, GRIM-19, Gene associated with retinoic interferon induced mortality 19 protein, Gene associated with retinoic and interferon-induced mortality 19 protein, Gene associated with retinoic and IFN-induced mortality 19 protein, FLJ59191, FLJ58045, Complex I-B16.6, CI-B16.6, CGI39 protein, CGI-39, Cell death regulatory protein GRIM-19, Cell death regulatory protein, CDA016, B16.6, AU022060, 2700054G14Rik |
| Ig Type | IgG |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of GRIM19 on MCF-7 cell using anti-GRIM19 antibody at 1/1,000 dilution. 2. Immunohistochemical analysis of paraffin-embedded human prostate cancer tissue using anti-GRIM19 antibody. Counter stained with hematoxylin. 3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-GRIM19 antibody. Counter stained with hematoxylin. 4. Immunohistochemical analysis of paraffin-embedded human liver tissue using anti-GRIM19 antibody. Counter stained with hematoxylin. 5. ICC staining GRIM19 in HepG2 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:500-1000; IHC: 1:50-200; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The GRIM family of proteins appear to be novel types of tumor suppressors. Grim19, which stands for gene associated with retinoic-interferon-induced mortality 19 protein, is also designated cell death-regulatory protein Grim-19 or NADH dehydrogenase ubiquinone 1 alpha subcomplex subunit 13. The Grim19 protein plays two roles within the cell. As a member of the interferon-beta and retinoic acid-induced pathway of cell death, Grim19 induces apoptosis. As part of the mitochondrial complex I, Grim19 is essential for its assembly and electron transfer activity. It transfers electrons to the respiratory chain from NADH and plays a role in the interferon/all-trans-retinoic acid (IFN/RA) cell death pathway. It localizes primarily to the mitochondrion, but may translocate to the nucleus upon IFN/RA treatment. Grim19 may also be useful as a biological marker or target for drug development. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human GRIM19 aa 1-150 |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 17 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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