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Thioctamide

Name: Thioctamide
Brand: TargetMol
SKU: T0823
Price: 30 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T0823Cas No. 3206-73-3

Alias Thioctic acid amide, Lipoamide

Thioctamide (Thioctic acid amide) is a trivial name for 6, 8-dithiooctanoic amide. It is 6, 8-dithiooctanoic acid's functional form where the carboxyl group is attached to protein (or any other amine) by an amide linkage (containing -NH2).

Thioctamide

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Purity: 99.47%

Catalog No. T0823Alias Thioctic acid amide, LipoamideCas No. 3206-73-3

Pack Size	Price	USA Warehouse	Global Warehouse
10 mg	$30	In Stock	In Stock
25 mg	$41	In Stock	In Stock
50 mg	$65	In Stock	In Stock
100 mg	$86	In Stock	In Stock
200 mg	$121	In Stock	In Stock
1 mL x 10 mM (in DMSO)	$30	In Stock	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

Questions

Batch Information

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Purity:99.47%

Appearance:Solid

Color:White

Resource Download

COA HNMR HPLC LCMS

Product Introduction

Bioactivity

Description	Thioctamide (Thioctic acid amide) is a trivial name for 6, 8-dithiooctanoic amide. It is 6, 8-dithiooctanoic acid's functional form where the carboxyl group is attached to protein (or any other amine) by an amide linkage (containing -NH2).
Synonyms	Thioctic acid amide, Lipoamide

Chemical Properties

Molecular Weight	205.34
Formula	C₈H₁₅NOS₂
Cas No.	3206-73-3
Smiles	NC(=O)CCCCC1CCSS1
Relative Density.	1.313g/cm3

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (267.85 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	4.8700 mL	24.3499 mL	48.6997 mL	243.4986 mL
5 mM	0.9740 mL	4.8700 mL	9.7399 mL	48.6997 mL
10 mM	0.4870 mL	2.4350 mL	4.8700 mL	24.3499 mL
20 mM	0.2435 mL	1.2175 mL	2.4350 mL	12.1749 mL
50 mM	0.0974 mL	0.4870 mL	0.9740 mL	4.8700 mL
100 mM	0.0487 mL	0.2435 mL	0.4870 mL	2.4350 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc