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Anti-SOCS2 Antibody (9S693) is a Rabbit antibody targeting SOCS2. Anti-SOCS2 Antibody (9S693) can be used in WB,ICC,IF,IP.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $297 | 7-10 days | |
100 μL | $497 | 7-10 days |
Description | Anti-SOCS2 Antibody (9S693) is a Rabbit antibody targeting SOCS2. Anti-SOCS2 Antibody (9S693) can be used in WB,ICC,IF,IP. |
Synonyms | Suppressor of cytokine signaling 2, STAT-induced STAT inhibitor 2, STATI2, STATI 2, STAT induced STAT inhibitor 2, SSI-2, SSI2, SSI 2, SOCS2_HUMAN, SOCS-2, Socs2, SOCS 2, Cytokine-inducible SH2 protein 2, Cytokine inducible SH2 protein 2, Cish2, Cish 2, CIS-2, CIS2, CIS 2 |
Ig Type | IgG |
Clone | 9S693 |
Reactivity | Human |
Verified Activity | 1. Western blot analysis of SOCS2 on different lysates using anti-SOCS2 antibody at 1/1,000 dilution. Positive control:Lane 1: Human placenta Lane 2: SH-SY-5Y 2. ICC staining SOCS2 in LOVO cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining SOCS2 in PC-3M cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 4. ICC staining SOCS2 in SH-SY-5Y cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
Application | |
Recommended Dose | WB: 1:500-2000; ICC: 1:50-200; IP: 1:10-50 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS2 appears to be a negative regulator in the growth hormone/IGF1 signaling pathway. Probable substrate recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein: human SOCS2 1-150aa |
Antigen Species | human |
Uniprot ID |
Molecular Weight | Theoretical: 22 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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