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Flavin adenine dinucleotide

Name: Flavin adenine dinucleotide
Brand: TargetMol
SKU: T65172
Price: 37 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T65172Cas No. 146-14-5

Alias FAD

Flavin adenine dinucleotide (FAD) is a REDOX cofactor and protein cogroup involved in various metabolic reactions.

Flavin adenine dinucleotide

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Purity: 99.98%

Catalog No. T65172Alias FADCas No. 146-14-5

Flavin adenine dinucleotide (FAD) is a REDOX cofactor and protein cogroup involved in various metabolic reactions.

Pack Size	Price	USA Warehouse	Global Warehouse
5 mg	$37	In Stock	In Stock
10 mg	$53	In Stock	In Stock
25 mg	$88	In Stock	In Stock
50 mg	$129	In Stock	In Stock
100 mg	$192	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

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Purity:99.98%

Appearance:Solid

Color:Yellow to Orange

Resource Download

COA LCMS HNMR

Product Introduction

Bioactivity

Description	Flavin adenine dinucleotide (FAD) is a REDOX cofactor and protein cogroup involved in various metabolic reactions.
In vitro	Characterized by an additional polymer-type redox reaction, Poly(Flavin adenine dinucleotide, FAD) is a highly effective electrocatalyst for NADH oxidation. Operating at the lowest potentials reported for NADH transducers (0.00 V, pH 7.4), poly(FAD) exhibits an electrochemical rate constant of 1.8 ± 0.6×10-3 cm/s, which is at the level of the NADH mass-transfer constant. Poly(FAD)-modified electrodes demonstrate dramatically improved stability and are the most advantageous NADH transducers for analytical chemistry[2].
In vivo	Administered intravenously at a dose of 2 mg/kg, Flavin adenine dinucleotide significantly cancels the chlorpromazine (CPZ)-induced decrease in ventricular fibrillation threshold (VFT). The effect of CPZ on canine heart mitochondria is nullified by Flavin adenine dinucleotide. Following the injection of Flavin adenine dinucleotide, the dogs experience a transient hypotension within 10 minutes, after which their blood pressures recover to the initial level. Additionally, Flavin adenine dinucleotide prevents mitochondrial dysfunction induced by chlorpromazine[1].
Synonyms	FAD

Chemical Properties

Molecular Weight	785.55
Formula	C₂₇H₃₃N₉O₁₅P₂
Cas No.	146-14-5
Smiles	C([C@@H]([C@@H]([C@@H](COP(OP(OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)N2C=3C(N=C2)=C(N)N=CN3)(=O)O)(=O)O)O)O)O)N4C=5C(=NC=6C4=CC(C)=C(C)C6)C(=O)NC(=O)N5

Storage & Solubility Information

Storage

keep away from direct sunlight,store at low temperature | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

H2O: 125 mg/mL (159.12 mM), Sonication is recommended.

Solution Preparation Table

H2O

	1mg	5mg	10mg	50mg
1 mM	1.2730 mL	6.3650 mL	12.7299 mL	63.6497 mL
5 mM	0.2546 mL	1.2730 mL	2.5460 mL	12.7299 mL
10 mM	0.1273 mL	0.6365 mL	1.2730 mL	6.3650 mL
20 mM	0.0636 mL	0.3182 mL	0.6365 mL	3.1825 mL
50 mM	0.0255 mL	0.1273 mL	0.2546 mL	1.2730 mL
100 mM	0.0127 mL	0.0636 mL	0.1273 mL	0.6365 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc