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Anti-SAMHD1 Antibody (8T611)
(Synonyms: SBBI88, Samhd 1, SAMH1_HUMAN, SAM domain and HD domain-containing protein 1, SAM domain and HD domain containing protein 1, SAM domain and HD domain 1, OTTHUMP00000030889, MOP-5, MOP5, MOP 5, Monocyte protein 5, Mg11, HDDC1, HD domain containing 1, dNTPase, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, Dendritic cell-derived IFNG-induced protein, Dendritic cell derived IFNG induced protein, DCIP, CHBL2) Copy Product Info
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Synonyms: SBBI88, Samhd 1, SAMH1_HUMAN, SAM domain and HD domain-containing protein 1, SAM domain and HD domain containing protein 1, SAM domain and HD domain 1, OTTHUMP00000030889, MOP-5, MOP5, MOP 5, Monocyte protein 5, Mg11, HDDC1, HD domain containing 1, dNTPase, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, Dendritic cell-derived IFNG-induced protein, Dendritic cell derived IFNG induced protein, DCIP, CHBL2
Catalog No. TMAC-03684 Copy Product Info
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Anti-SAMHD1 Antibody (8T611) is a Rabbit antibody targeting SAMHD1. Anti-SAMHD1 Antibody (8T611) can be used in FCM,ICC,IHC,WB.
Anti-SAMHD1 Antibody
(8T611)
(8T611)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-SAMHD1 Antibody (8T611) is a Rabbit antibody targeting SAMHD1. Anti-SAMHD1 Antibody (8T611) can be used in FCM,ICC,IHC,WB. |
| Synonyms | SBBI88, Samhd 1, SAMH1_HUMAN, SAM domain and HD domain-containing protein 1, SAM domain and HD domain containing protein 1, SAM domain and HD domain 1, OTTHUMP00000030889, MOP-5, MOP5, MOP 5, Monocyte protein 5, Mg11, HDDC1, HD domain containing 1, dNTPase, Deoxynucleoside triphosphate triphosphohydrolase SAMHD1, Dendritic cell-derived IFNG-induced protein, Dendritic cell derived IFNG induced protein, DCIP, CHBL2 |
| Ig Type | IgG |
| Clone | 8T611 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB: 1:500-2000; IHC: 1:50-200; ICC: 1:100-500; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | SAM domain and HD domain-containing protein 1 is a protein that in humans is encoded by the SAMHD1 gene. SAMHD1 is a cellular enzyme, responsible for blocking replication of HIV in dendritic cells, macrophages and monocytes. It is an enzyme that exhibits phosphohydrolase activity, converting deoxynucleoside triphosphates (dNTPs) to inorganic phosphate (iPPP) and a 2'-deoxynucleoside (i.e. deoxynucleosides without a phosphate group). In doing so, SAMHD1 depletes the pool of dNTPs available to a reverse transcriptase for viral cDNA synthesis and thus prevents viral replication. SAMHD1 has also shown nuclease activity. Although a ribonuclease activity was described to be required for HIV-1 restriction, recent data confirmed that SAMHD1-mediated HIV-1 restriction in cells does not involve ribonuclease activity. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 72 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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