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Anti-Sting Antibody (5Y781) is a Rabbit antibody targeting Sting. Anti-Sting Antibody (5Y781) can be used in FCM,ICC/IF,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
| Description | Anti-Sting Antibody (5Y781) is a Rabbit antibody targeting Sting. Anti-Sting Antibody (5Y781) can be used in FCM,ICC/IF,WB. |
| Synonyms | TMEM173, sting, Stimulator of interferon genes protein, Mediator of IRF3 activation |
| Ig Type | IgG |
| Clone | 5Y781 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of TMEM173 on U937 (1) and 293 (2) cell lysate using anti-TMEM173 antibody at 1/1,000 dilution. 2. Flow cytometric analysis of THP-1 cells with TMEM173 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). ![]() ![]() |
| Application | |
| Recommended Dose | WB: 1:500-1000; ICC/IF: 1:10-50; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Facilitator of innate immune signaling that promotes the production of type I interferon (IFN-alpha and IFN-beta). Innate immune response is triggered in response to non-CpG double-stranded DNA from viruses and bacteria delivered to the cytoplasm. Able to activate both NF-kappa-B and IRF3 transcription pathways to induce expression of type I interferon and exert a potent viral state following expression. May be involved in translocon function, the translocon possibly being able to influence the induction of type I interferons. May be involved in transduction of apoptotic signals via its association with the major histocompatibility complex class II (MHC-II). Mediates death signaling via activation of the extracellular signal-regulated kinase (ERK) pathway. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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