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Anti-MEIS2 Antibody (3Y477) is a Rabbit antibody targeting MEIS2. Anti-MEIS2 Antibody (3Y477) can be used in WB,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $296 | 7-10 days | |
100 μL | $498 | 7-10 days |
Description | Anti-MEIS2 Antibody (3Y477) is a Rabbit antibody targeting MEIS2. Anti-MEIS2 Antibody (3Y477) can be used in WB,FCM. |
Synonyms | TALE homeobox protein Meis2, MRG1, MGC2820, MEIS2_HUMAN, MEIS2, Meis1-related protein 1, Meis1 related protein 1, Meis1 related gene 1, Meis1 myeloid ecotropic viral integration site 1 homolog 2 (mouse), Meis1 myeloid ecotropic viral integration site 1 homolog 2, Meis homolog 2, Meis homeobox 2, MEIS 2, Meis (mouse) homolog 2, HsT18361, Homeobox protein Meis2 |
Ig Type | IgG |
Reactivity | Human,Mouse |
Verified Activity | 1. Western blot analysis of MEIS2 on different lysates using anti-MEIS2 antibody at 1/500 dilution. Positive control: Lane 1: Mouse testis, Lane 2: SH-SY-5Y, Lane 3: Mouse lung. 2. Flow cytometric analysis of K562 cells with MEIS2 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti-rabbit IgG was used as the secondary antibody. |
Application | |
Recommended Dose | WB: 1:500-1000; FCM: 1:50-100 |
Antibody Type | Monoclonal |
Host Species | Rabbit |
Construction | Recombinant Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Profilins regulate Actin polymerization by binding to and sequestering the Actin monomer. Profilins act as a nucleotide exchange factor that charges Actin with ATP after binding the Actin monomer through a 1:1 stoichiometric relationship. Human Profilin-1 and Profilin-2 are encoded by two separate genes mapping to chromosomes 17p13.2 and 3q25.1, respectively. Both Profilin-1 and Profilin-2 are abundantly expressed in kidney. Profilin-1 is highly expressed in lung, liver, placenta and kidney while Profilin-2 is highly expressed in brain and skeletal muscle. In axonal and dendritic processes of mouse brain, Profilins co-localize with dynamin I and synapsin. Profilin may play a role in mediating cell adhesion. The overexpression of Profilin in endothelial cells results in increased adhesion to Fibronectin. In food allergy, plant Profilin is considered a pan-allergen. Case studies indicate individuals with allergies to various foods including celery, carrots, zucchini and peanuts are actually sensitive to the Profilin proteins in these foods. |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 51 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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