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Anti-CRTC3 Antibody (9Y361)
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Catalog No. TMAH-00301
Alias Transducer of regulated cAMP response element-binding protein 3, Transducer of CREB protein 3, TORC-3, TORC3, CREB-regulated transcription coactivator 3
Anti-CRTC3 Antibody (9Y361) is an antibody targeting CRTC3. Anti-CRTC3 Antibody (9Y361) can be used in ELISA,IHC.
Anti-CRTC3 Antibody (9Y361)
Anti-CRTC3 Antibody (9Y361)
😃Good
Catalog No. TMAH-00301Alias Transducer of regulated cAMP response element-binding protein 3, Transducer of CREB protein 3, TORC-3, TORC3, CREB-regulated transcription coactivator 3
Anti-CRTC3 Antibody (9Y361) is an antibody targeting CRTC3. Anti-CRTC3 Antibody (9Y361) can be used in ELISA,IHC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $348 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-CRTC3 Antibody (9Y361) is an antibody targeting CRTC3. Anti-CRTC3 Antibody (9Y361) can be used in ELISA,IHC. |
| Synonyms | Transducer of regulated cAMP response element-binding protein 3, Transducer of CREB protein 3, TORC-3, TORC3, CREB-regulated transcription coactivator 3 |
| Ig Type | Rabbit IgG |
| Clone | 9Y361 |
| Reactivity | Human |
| Verified Activity | IHC image of TMAH-00301 diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB. |
| Application | |
| Recommended Dose | IHC:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. Cytoplasm. |
| Tissue Specificity | Predominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR). |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human CRTC3 |
| Antigen Species | Human |
| Gene Name | CRTC3 |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Microbiology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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