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Anti-CRTC3 Antibody (9Y361) (Synonyms: Transducer of regulated cAMP response element-binding protein 3, Transdu...)

Catalog No. TMAH-00301 Copy Product Info
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Anti-CRTC3 Antibody (9Y361) is an antibody targeting CRTC3. Anti-CRTC3 Antibody (9Y361) can be used in ELISA,IHC.

Anti-CRTC3 Antibody (9Y361)

Copy Product Info
🥰Excellent
Catalog No. TMAH-00301
Synonyms Transducer of regulated cAMP response element-binding protein 3, Transducer of CREB protein 3, TORC-3, TORC3, CREB-regulated transcription coactivator 3

Anti-CRTC3 Antibody (9Y361) is an antibody targeting CRTC3. Anti-CRTC3 Antibody (9Y361) can be used in ELISA,IHC.

Anti-CRTC3 Antibody
(9Y361)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2097-10 days7-10 days
100 μL$3487-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-CRTC3 Antibody (9Y361) is an antibody targeting CRTC3. Anti-CRTC3 Antibody (9Y361) can be used in ELISA,IHC.
SynonymsTransducer of regulated cAMP response element-binding protein 3, Transducer of CREB protein 3, TORC-3, TORC3, CREB-regulated transcription coactivator 3
Ig Type
Rabbit IgG
Clone
9Y361
Reactivity
Human
Verified Activity
IHC image of TMAH-00301 diluted at 1:100 and staining in paraffin-embedded human testis tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a Goat anti-rabbit polymer IgG labeled by HRP and visualized using 0.05% DAB.
Application
Recommended Dose
IHC:1:50-1:200.
Antibody Type
Monoclonal
Subcellular LocalizationNucleus. Cytoplasm.
Tissue SpecificityPredominantly expressed in B and T lymphocytes. Highest levels in lung. Also expressed in brain, colon, heart, kidney, ovary, and prostate. Weak expression in liver, pancreas, muscle, small intestine, spleen and stomach.
ConstructionRecombinant Antibody
PurificationAffinity-chromatography
AppearanceLiquid
FormulationPhosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Research BackgroundTranscriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
A synthetic peptide: Human CRTC3
Antigen Species
Human
Gene Name
CRTC3
Gene ID
Uniprot ID
Biology Area
Epigenetics and Nuclear Signaling, Microbiology
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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