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Anti-KDM6A Antibody (8V883) is a Mouse antibody targeting KDM6A. Anti-KDM6A Antibody (8V883) can be used in WB,FCM.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
50 μL | $298 | 7-10 days | |
100 μL | $428 | 7-10 days |
Description | Anti-KDM6A Antibody (8V883) is a Mouse antibody targeting KDM6A. Anti-KDM6A Antibody (8V883) can be used in WB,FCM. |
Synonyms | UTX, Ubiquitously-transcribed X chromosome tetratricopeptide repeat protein, Ubiquitously-transcribed TPR protein on the X chromosome, Ubiquitously transcribed X chromosome tetratricopeptide repeat protein, Ubiquitously transcribed TPR protein on the X chromosome, Ubiquitously transcribed TPR gene on the X chromosome, Ubiquitously transcribed tetratricopeptide repeat X chromosome, Ubiquitously transcribed tetratricopeptide repeat protein X linked, MGC141941, Lysine-specific demethylase 6A, Lysine specific demethylase 6A ubiquitously transcribed tetratricopeptide repeat gene X chromosome, Lysine K specific demethylase 6A, Lysine (K) specific demethylase 6A, KDM6A_HUMAN, Kdm 6a, KABUK2, Histone demethylase UTX, DKFZp686A03225, bA386N14.2 ubiquitously transcribed X chromosome tetratricopeptide repeat protein UTX, bA386N14.2 (ubiquitously transcribed X chromosome tetratricopeptide repeat protein (UTX), bA386N14.2 |
Clone | 8V883 |
Reactivity | Human |
Verified Activity | 1. Western blot analysis of KDM6A on human KDM6A recombinant protein using anti-KDM6A antibody at 1/1,000 dilution. 2. Western blot analysis of KDM6A on HEK293 (1) and KDM6A-hIgGFc transfected HEK293 (2) cell lysate using anti-KDM6A antibody at 1/1,000 dilution. 3. Flow cytometric analysis of Hela cells with KDM6A antibody at 1/100 dilution (green) compared with an unlabelled control (cells without incubation with primary antibody; red). |
Application | |
Recommended Dose | WB: 1:500-2000; FCM: 1:100-200 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | Hybridoma Monoclonal Antibody |
Purification | ProA affinity purified |
Appearance | Liquid |
Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
Research Background | Histone demethylase that specifically demethylates 'Lys-27' of histone H3, thereby playing a central role in histone code . Demethylates trimethylated and dimethylated but not monomethylated H3 'Lys-27' . Plays a central role in regulation of posterior development, by regulating HOX gene expression. Demethylation of 'Lys-27' of histone H3 is concomitant with methylation of 'Lys-4' of histone H3, and regulates the recruitment of the PRC1 complex and monoubiquitination of histone H2A . |
Conjucates | Unconjugated |
Immunogen | Recombinant Protein |
Uniprot ID |
Molecular Weight | Theoretical: 154 kDa. |
Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
Transport | Shipping with blue ice. |
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