Arimoclomol citrate

Name: Arimoclomol citrate
Brand: TargetMol
SKU: T40468
Rating: 4.5 (1 reviews)

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Catalog No. T40468Cas No. 368860-21-3

Alias BRX-220 citrate, Arimoclomol citrate

Arimoclomol citrate (BRX-220 citrate) is a heat shock protein (HSP) co-inducer that enhances Hsp expression, impacts protein aggregation, clears misfolded assemblies, and interacts with the proteasome-ubiquitin system. This compound is known for its ability to protect motor neurons.

Arimoclomol citrate

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Catalog No. T40468Alias BRX-220 citrate, Arimoclomol citrateCas No. 368860-21-3

Pack Size	Price	USA Warehouse	Global Warehouse	Quantity
25 mg	$1,520	Backorder	Backorder

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Expected start date of shipmentUSA Warehouse [1-2 days] Global Warehouse [5-7 days]

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Product Introduction

Bioactivity

Description	Arimoclomol citrate (BRX-220 citrate) is a heat shock protein (HSP) co-inducer that enhances Hsp expression, impacts protein aggregation, clears misfolded assemblies, and interacts with the proteasome-ubiquitin system. This compound is known for its ability to protect motor neurons.
In vivo	Arimoclomol (BRX-220; 20 mg/kg; orally administered for 5 days) demonstrated a protective effect against cholecystokinin-octapeptide (CCK)-induced acute pancreatitis in male Wistar rats (240-270 g).
Synonyms	BRX-220 citrate, Arimoclomol citrate

Chemical Properties

Molecular Weight	505.91
Formula	C₂₀H₂₈ClN₃O₁₀
Cas No.	368860-21-3
Relative Density.	no data available

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

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Please enter your animal experiment information in the following box and click Calculate to obtain the mother liquor preparation method and in vivo formula preparation method:

For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . TargetMol | Animal experiments

A total of 10 animals were administered, and the formula you used is 5% TargetMol | reagent

DMSO+30% PEG300+5% Tween 80+60% Saline/PBS/ddH₂O. So your working solution concentration is 2 mg/mL。

Mother liquor preparation method: 2 mg of drug dissolved in 50 μL DMSO TargetMol | reagent

(mother liquor concentration of 40 mg/mL), if you need to configure a concentration that exceeds the solubility of the product, please contact us first.

Preparation method for in vivo formula: Take 50 μL DMSO TargetMol | reagent

main solution, add 300 μLPEG300 TargetMol | reagent

mix well and clarify, then add 50 more μL Tween 80, mix well and clarify, then add 600 more μLSaline/PBS/ddH₂O TargetMol | reagent

mix well and clarify

For Reference Only. Please develop an appropriate dissolution method based on your laboratory animals and route of administration.

All types of co-solvents required for the protocol, such asDMSO, PEG300/ PEG400, Tween 80, SBE-β-CD, corn oil are available for purchase on the TargetMol website with a simple click.

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