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Anti-KAT8 Antibody (7Z632)

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Catalog No. TMAC-02298

Anti-KAT8 Antibody (7Z632) is a Rabbit antibody targeting KAT8. Anti-KAT8 Antibody (7Z632) can be used in WB,ICC,IF,IHC,IP,FCM.

Anti-KAT8 Antibody (7Z632)

Anti-KAT8 Antibody (7Z632)

😃Good
Catalog No. TMAC-02298
Anti-KAT8 Antibody (7Z632) is a Rabbit antibody targeting KAT8. Anti-KAT8 Antibody (7Z632) can be used in WB,ICC,IF,IHC,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4967-10 days
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Product Introduction

Bioactivity
Description
Anti-KAT8 Antibody (7Z632) is a Rabbit antibody targeting KAT8. Anti-KAT8 Antibody (7Z632) can be used in WB,ICC,IF,IHC,IP,FCM.
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Application
Recommended Dose
IHC: 1:50-1:200; ICC: 1:50-1:200; FCM: 1:50-1:100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
FormulationRabbit IgG in 10mM phosphate buffered saline , pH 7.4, 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
Research BackgroundDosage compensation ensures that males with a single X chromosome and females with two X chromosomes have the same amount of most X-linked gene products. In Drosophila, this is acheived by enhancing the level of transcription of the X chromosome in males. Proteins such as maleless, male specific lethal 1, 2 and 3, and males absent on the first (MOF) form a dosage compensation complex (DCC) that is required for the twofold increase of transcription of the male X chromosome. The DCC is preferentially associated with many sites on the X chromosome in somatic cells of males. The binding of the DCC to the X chromosome is dependent upon histone 4 acetylation at lysine 16, which is accomplished by MOF. In mammals, MOF (also designated hMOF, MYST1, or MOZ) belongs to the MYST family of histone acetyl transferases which are characterized by a unique C2HC-type zinc finger close to their HAT domains. MOF utilizes the zinc finger domain to contact the globular part of the nucleosome as well as the histone H4 N-terminal tail substrate. The carboxy terminal domain of human MOF also has histone acetyltransferase activity directed against histones H3 and H2A, a characteristic shared with other MYST family histone acetyltransferases.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: within N-terminal human KAT8
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 52 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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