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Anti-SIN3A Antibody (8K338)
(Synonyms: Transcriptional corepressor Sin3a, Paired amphipathic helix protein Sin3a, Histone deacetylase complex subunit Sin3a) Copy Product Info
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Synonyms: Transcriptional corepressor Sin3a, Paired amphipathic helix protein Sin3a, Histone deacetylase complex subunit Sin3a
Catalog No. TMAH-01090 Copy Product Info
🥰Excellent
Anti-SIN3A Antibody (8K338) is an antibody targeting SIN3A. Anti-SIN3A Antibody (8K338) can be used in ELISA,IF,IHC,WB.
Anti-SIN3A Antibody
(8K338)
(8K338)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $208 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
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Chemical Properties
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| Description | Anti-SIN3A Antibody (8K338) is an antibody targeting SIN3A. Anti-SIN3A Antibody (8K338) can be used in ELISA,IF,IHC,WB. |
| Synonyms | Transcriptional corepressor Sin3a, Paired amphipathic helix protein Sin3a, Histone deacetylase complex subunit Sin3a |
| Ig Type | Rabbit IgG |
| Clone | 8K338 |
| Reactivity | Human |
| Application | |
| Recommended Dose | WB:1:500-1:5000; IHC:1:50-1:200; IF:1:20-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Nucleus. Nucleus, nucleolus. Note=Recruited to the nucleolus by SAP30L. |
| Tissue Specificity | Expressed in the developing brain, with highest levels of expression detected in the ventricular zone of various cortical regions. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA. Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation. Involved in the control of the circadian rhythms. Required for the transcriptional repression of circadian target genes, such as PER1, mediated by the large PER complex through histone deacetylation. Cooperates with FOXK1 to regulate cell cycle progression probably by repressing cell cycle inhibitor genes expression. Required for cortical neuron differentiation and callosal axon elongation. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human mSin3A |
| Antigen Species | Human |
| Gene Name | SIN3A |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Epigenetics and Nuclear Signaling, Cancer, Metabolism |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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