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Anti-ROCK1 Antibody (4X563)

😃Good
Catalog No. TMAC-03616
Alias ROCK 1, Rho associated protein kinase 1, Rho associated coiled coil containing protein kinase 1, Renal carcinoma antigen NY REN 35, p160ROCK, p160 ROCK1

Anti-ROCK1 Antibody (4X563) is a Rabbit antibody targeting ROCK1. Anti-ROCK1 Antibody (4X563) can be used in WB,ICC/IF,IHC,IP,FCM.

Anti-ROCK1 Antibody (4X563)

Anti-ROCK1 Antibody (4X563)

😃Good
Catalog No. TMAC-03616Alias ROCK 1, Rho associated protein kinase 1, Rho associated coiled coil containing protein kinase 1, Renal carcinoma antigen NY REN 35, p160ROCK, p160 ROCK1
Anti-ROCK1 Antibody (4X563) is a Rabbit antibody targeting ROCK1. Anti-ROCK1 Antibody (4X563) can be used in WB,ICC/IF,IHC,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-ROCK1 Antibody (4X563) is a Rabbit antibody targeting ROCK1. Anti-ROCK1 Antibody (4X563) can be used in WB,ICC/IF,IHC,IP,FCM.
SynonymsROCK 1, Rho associated protein kinase 1, Rho associated coiled coil containing protein kinase 1, Renal carcinoma antigen NY REN 35, p160ROCK, p160 ROCK1
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of ROCK1 on different lysates using anti-ROCK1 antibody at 1/1,000 dilution. Positive control: Lane 1: A431, Lane 2: NIH/3T3.
2. Immunohistochemical analysis of paraffin-embedded mouse thyroid tissue using anti-ROCK1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-ROCK1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human thyroid tissue using anti-ROCK1 antibody. Counter stained with hematoxylin.
Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; ICC/IF: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundRho, the Ras-related small GTPase, is responsible for the regulation of Actin-based cytoskeletal structures including stress fibers, focal adhesions and the contractile ring apparatus. Rho proteins function as molecular switches that are able to turn cytokinesis on and off. Although little is known about signaling downstream of Rho, a host of putative Rho effector proteins have been described, including rhophilin, Rhotekin, citron and the serine/threonine kinase, protein kinase N. Two additional Rho-activated serine/threonine kinases have been described, designated Rock-1 and Rock-2 (also referred to as Roka, for Rho-associated coil-containing protein kinase). Rock-1 and Rock-2 share a structural similarity with myotonic dystrophy kinase.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 158 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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