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Anti-ATG12 Antibody (2H769)
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Catalog No. TMAH-00087
Alias Ubiquitin-like protein ATG12, HAPG12, FBR93, Autophagy-related protein 12, Autophagy 12, ATG12 autophagy related 12 homolog (S. cerevisiae), ATG12 autophagy related 12 homolog, ATG 12, APG12-like, APG12L
Anti-ATG12 Antibody (2H769) is an antibody targeting ATG12. Anti-ATG12 Antibody (2H769) can be used in ELISA.
Anti-ATG12 Antibody (2H769)
Anti-ATG12 Antibody (2H769)
😃Good
Catalog No. TMAH-00087Alias Ubiquitin-like protein ATG12, HAPG12, FBR93, Autophagy-related protein 12, Autophagy 12, ATG12 autophagy related 12 homolog (S. cerevisiae), ATG12 autophagy related 12 homolog, ATG 12, APG12-like, APG12L
Anti-ATG12 Antibody (2H769) is an antibody targeting ATG12. Anti-ATG12 Antibody (2H769) can be used in ELISA.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $209 | 7-10 days | |
| 100 μL | $348 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Antibody Type: Recombinant Rabbit Monoclonal Application: ELISA Reactivity: Human |
| Alias | Ubiquitin-like protein ATG12, HAPG12, FBR93, Autophagy-related protein 12, Autophagy 12, ATG12 autophagy related 12 homolog (S. cerevisiae), ATG12 autophagy related 12 homolog, ATG 12, APG12-like, APG12L |
| Ig Type | Rabbit IgG |
| Clone | 2H769 |
| Reactivity | Human |
| Application | ELISA |
| Antibody Type | Monoclonal |
| Subcellular Localization | Cytoplasm. Preautophagosomal structure membrane; Peripheral membrane protein. Note=TECPR1 recruits the ATG12-ATG5 conjugate to the autolysosomal membrane. |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. |
| Research Background | Ubiquitin-like protein involved in autophagy vesicles formation. Conjugation with ATG5 through a ubiquitin-like conjugating system involving also ATG7 as an E1-like activating enzyme and ATG10 as an E2-like conjugating enzyme, is essential for its function. The ATG12-ATG5 conjugate acts as an E3-like enzyme which is required for lipidation of ATG8 family proteins and their association to the vesicle membranes. (Microbial infection) May act as a proviral factor. In association with ATG5, negatively regulates the innate antiviral immune response by impairing the type I IFN production pathway upon vesicular stomatitis virus (VSV) infection. Required for the translation of incoming hepatitis C virus (HCV) RNA and, thereby, for the initiation of HCV replication, but not required once infection is established. |
| Conjucates | Unconjugated |
| Immunogen | A synthetic peptide: Human ATG12 |
| Antigen Species | Human |
| Gene ID | 9140 |
| Uniprot ID | |
| Biology Area | Cell Biology |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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