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Anti-MEK2 Antibody (8K565)

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Catalog No. TMAY-01055
Alias PRKMK2, MKK2, mitogen-activated protein kinase kinase 2, MEK2, MAPKK2, FLJ26075, CFC4

Anti-MEK2 Antibody (8K565) is a Mouse antibody targeting MEK2. Anti-MEK2 Antibody (8K565) can be used in ELISA.

Anti-MEK2 Antibody (8K565)

Anti-MEK2 Antibody (8K565)

😃Good
Catalog No. TMAY-01055Alias PRKMK2, MKK2, mitogen-activated protein kinase kinase 2, MEK2, MAPKK2, FLJ26075, CFC4
Anti-MEK2 Antibody (8K565) is a Mouse antibody targeting MEK2. Anti-MEK2 Antibody (8K565) can be used in ELISA.
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100 μL$199 7-10 days
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Product Introduction

Bioactivity
Description
Anti-MEK2 Antibody (8K565) is a Mouse antibody targeting MEK2. Anti-MEK2 Antibody (8K565) can be used in ELISA.
AliasPRKMK2, MKK2, mitogen-activated protein kinase kinase 2, MEK2, MAPKK2, FLJ26075, CFC4
Ig Type
Monoclonal Mouse IgG2b
Clone
8K565
Reactivity
Human
Application
ELISA
Recommended Dose
ELISA: 1:1000-1:2000
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionThis antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human MEK2/MAP2K2/MKK2 (rh MEK2/MAP2K2/MKK2; TMPY-04544; NP_109587.1; Met1-Val400). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography.
PurificationProtein A
AppearanceLiquid
Formulation0.2 μm filtered solution in PBS
Research BackgroundDual specificity mitogen-activated protein kinase kinase 2, also known as MAP kinase kinase 2, MAPKK2, ERK activator kinase 2, MAPK / ERK kinase 2, MEK2 and MAP2K2, is a member of the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase subfamily. MAP2K2 / MEK2 contains one protein kinase domain. MEK1 and MEK2 (also known as MAP2K1 and MAP2K2, respectively) are evolutionarily conserved, dual-specificity kinases that mediate Erk1 and Erk2 activation during adhesion and growth factor signaling. MAP2K1 / MEK1 is a crucial modulator of Mek and Erk signaling and have potential implications for the role of MEK1 and MEK2 in tumorigenesis. MAP2K2 / MEK2 catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. It also activates the ERK1 and ERK2 MAP kinases. Defects in MAP2K2 are a cause of Cardiofaciocutaneous Syndrome (CFC Syndrome) which is characterized by a distinctive facial appearance, heart defects, and mental retardation. Heart defects include pulmonic stenosis, atrial septal defects, and hypertrophic cardiomyopathy.Cancer ImmunotherapyImmune CheckpointImmunotherapyTargeted Therapy
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Human MEK2/MAP2K2/MKK2 Protein (TMPY-04544)
Antigen Species
Human
Biology Area
Cancer Drug Targets
Chemical Properties
Stability & Storage
Stability & StorageStore at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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