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Anti-GCSH Antibody (9I138) is a Rabbit antibody targeting GCSH. Anti-GCSH Antibody (9I138) can be used in ELISA.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 100 μL | $269 | 7-10 days | 7-10 days |
| Description | Anti-GCSH Antibody (9I138) is a Rabbit antibody targeting GCSH. Anti-GCSH Antibody (9I138) can be used in ELISA. |
| Synonyms | NKH, glycine cleavage system protein H (aminomethyl carrier), GCE |
| Ig Type | Rabbit IgG |
| Clone | 9I138 |
| Reactivity | Human |
| Specificity | Human GCSH |
| Application | |
| Recommended Dose | ELISA: 1:5000-1:10000 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | This antibody was obtained from a rabbit immunized with purified, recombinant Human GCSH (rh GCSH; TMPY-03503; AAA36011.1; Ser49-Glu173). |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | Degradation of glycine is brought about by the glycine cleavage system, which is composed of four mitochondrial protein components: P protein (a pyridoxal phosphate-dependent glycine decarboxylase), H protein (a lipoic acid-containing protein), T protein (a tetrahydrofolate-requiring enzyme), and L protein (a lipoamide dehydrogenase). GCSH is the H protein, which transfers the methylamine group of glycine from the P protein to the T protein. Defects in GCSH gene are a cause of nonketotic hyperglycinemia (NKH). Two transcript variants, one protein-coding and the other probably not protein-coding,have been found for GCSH gene. Also, several transcribed and non-transcribed pseudogenes of GCSH gene exist throughout the genome. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human GCSH Protein (TMPY-03503) |
| Antigen Species | Human |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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