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(R)-TCO-OH is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Pack Size | Price | Availability | Quantity |
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100 mg | Inquiry | Backorder | |
500 mg | Inquiry | Backorder |
Description | (R)-TCO-OH is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. |
In vitro | PROTACs consist of two distinct ligands joined by a linker: one targeting an E3 ubiquitin ligase and the other binding the target protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade these target proteins[1]. |
Molecular Weight | 126.2 |
Formula | C8H14O |
Cas No. | 39637-78-0 |
Storage | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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