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Anti-BAX Antibody (1J827) (Synonyms: Bcl-2-like protein 4, Bcl2-L-4, BCL2L4, Apoptosis regulator BAX)

Catalog No. TMAC-00383 Copy Product Info
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Anti-BAX Antibody (1J827) is a Rabbit antibody targeting BAX. Anti-BAX Antibody (1J827) can be used in FCM,IHC,IP,WB.

Anti-BAX Antibody (1J827)

Copy Product Info
🥰Excellent
Catalog No. TMAC-00383
Synonyms Bcl-2-like protein 4, Bcl2-L-4, BCL2L4, Apoptosis regulator BAX

Anti-BAX Antibody (1J827) is a Rabbit antibody targeting BAX. Anti-BAX Antibody (1J827) can be used in FCM,IHC,IP,WB.

Anti-BAX Antibody
(1J827)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2967-10 days7-10 days
100 μL$4967-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-BAX Antibody (1J827) is a Rabbit antibody targeting BAX. Anti-BAX Antibody (1J827) can be used in FCM,IHC,IP,WB.
SynonymsBcl-2-like protein 4, Bcl2-L-4, BCL2L4, Apoptosis regulator BAX
Ig Type
IgG
Clone
1J827
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of Bax on different lysates using anti-Bax antibody at 1/1,000 dilution. Positive control: Lane 1: Hela, Lane 2: MCF-7, Lane 3: Human liver.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-Bax antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human liver cancer tissue using anti-Bax antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human breast carcinoma tissue using anti-Bax antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse prostate tissue using anti-Bax antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse kidney tissue using anti-Bax antibody. Counter stained with hematoxylin.
7. Immunohistochemical analysis of paraffin-embedded mouse skin tissue using anti-Bax antibody. Counter stained with hematoxylin.
8. Flow cytometric analysis of Hela cells with Bax antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.
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Application
Recommended Dose
WB: 1:1000-5000; IHC: 1:50-200; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundThe Bcl-2 gene was isolated at the chromosomal breakpoint of t-bearing follicular B cell lymphomas. Bcl-2 blocks cell death following a variety of stimuli and confers a death-sparing effect to certain hematopoietic cell lines following growth factor withdrawal. Bcl-2 is localized to outer mitochondrial membranes and endoplasmic reticulum as well as nuclear membranes. A related protein, designated Bax (Bcl-associated X protein), has extensive amino acid homology with Bcl-2 and both homodimerizes and forms heterodimers with Bcl-2. Overexpression of Bax accelerates apoptotic death induced by cytokine deprivation in an IL-3 dependent cell line and Bax also counters the death repressor activity of Bcl-2.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 21 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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