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Anti-Fbx32 Antibody (6J554) (Alias: Muscle atrophy F box protein, Muscle atrophy F box, MGC33610, MGC13764...)

Catalog No. TMAC-01450 Copy Product Info
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Anti-Fbx32 Antibody (6J554) is a Rabbit antibody targeting Fbx32. Anti-Fbx32 Antibody (6J554) can be used in ICC,WB.

Anti-Fbx32 Antibody (6J554)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01450
Alias Muscle atrophy F box protein, Muscle atrophy F box, MGC33610, MGC137646, MGC108443, MAFbx, FLJ32424, FBXO32, fbxo25, Fbx32, F-box protein 32, F-box only protein 32, F box only protein 32, Atrophy gene 1, Atrogin-1, ATROGIN1, Atrogin 1, AI430017, 4833442G10Rik

Anti-Fbx32 Antibody (6J554) is a Rabbit antibody targeting Fbx32. Anti-Fbx32 Antibody (6J554) can be used in ICC,WB.

Anti-Fbx32 Antibody
(6J554)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2977-10 days7-10 days
100 μL$4967-10 days7-10 days
In stock · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-Fbx32 Antibody (6J554) is a Rabbit antibody targeting Fbx32. Anti-Fbx32 Antibody (6J554) can be used in ICC,WB.
SynonymsMuscle atrophy F box protein, Muscle atrophy F box, MGC33610, MGC137646, MGC108443, MAFbx, FLJ32424, FBXO32, fbxo25, Fbx32, F-box protein 32, F-box only protein 32, F box only protein 32, Atrophy gene 1, Atrogin-1, ATROGIN1, Atrogin 1, AI430017, 4833442G10Rik
Ig Type
IgG
Clone
6J554
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of Fbx32 on mouse skeletal muscle tissue using anti-Fbx32 antibody at 1/1,000 dilution.
2. ICC staining Fbx32 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
3. ICC staining Fbx32 in L6 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS.
verifiedActivityverifiedActivityverifiedActivity
Application
Recommended Dose
WB: 1:500-1000; ICC: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundMuscle atrophy F-box (MAFbx) is an E3 ubiquitin ligase that initiates ATP-dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. MAFbx transcript is abundant in cardiac and skeletal muscle undergoing atrophy. MAFbx -/- mice are resistant to muscle atrophy. MAFbx is thought to recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation during skeletal muscle atrophy. It interacts with MyoD by ubiquitination via a sequence found in transcriptional coactivators and therefore may play an important role in the course of muscle differentiation by determining the abundance of MyoD. MAFbx is specifically expressed in cardiac and skeletal muscle.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein: human Fbx32 1-200aa
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 41 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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