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Anti-Fbx32 Antibody (6J554)
😃Good
Catalog No. TMAC-01450
Alias Muscle atrophy F box protein, Muscle atrophy F box, MGC33610, MGC137646, MGC108443, MAFbx, FLJ32424, FBXO32, fbxo25, FBX32, Fbx32, F-box protein 32, F-box only protein 32, F box only protein 32, Atrophy gene 1, Atrogin-1, ATROGIN1, Atrogin 1, AI430017, 4833442G10Rik
Anti-Fbx32 Antibody (6J554) is a Rabbit antibody targeting Fbx32. Anti-Fbx32 Antibody (6J554) can be used in WB,ICC.
Anti-Fbx32 Antibody (6J554)
Anti-Fbx32 Antibody (6J554)
😃Good
Catalog No. TMAC-01450Alias Muscle atrophy F box protein, Muscle atrophy F box, MGC33610, MGC137646, MGC108443, MAFbx, FLJ32424, FBXO32, fbxo25, FBX32, Fbx32, F-box protein 32, F-box only protein 32, F box only protein 32, Atrophy gene 1, Atrogin-1, ATROGIN1, Atrogin 1, AI430017, 4833442G10Rik
Anti-Fbx32 Antibody (6J554) is a Rabbit antibody targeting Fbx32. Anti-Fbx32 Antibody (6J554) can be used in WB,ICC.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-Fbx32 Antibody (6J554) is a Rabbit antibody targeting Fbx32. Anti-Fbx32 Antibody (6J554) can be used in WB,ICC. |
| Synonyms | Muscle atrophy F box protein, Muscle atrophy F box, MGC33610, MGC137646, MGC108443, MAFbx, FLJ32424, FBXO32, fbxo25, FBX32, Fbx32, F-box protein 32, F-box only protein 32, F box only protein 32, Atrophy gene 1, Atrogin-1, ATROGIN1, Atrogin 1, AI430017, 4833442G10Rik |
| Ig Type | IgG |
| Clone | 6J554 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. Western blot analysis of Fbx32 on mouse skeletal muscle tissue using anti-Fbx32 antibody at 1/1,000 dilution. 2. ICC staining Fbx32 in A431 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. ICC staining Fbx32 in L6 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:500-1000; ICC: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Muscle atrophy F-box (MAFbx) is an E3 ubiquitin ligase that initiates ATP-dependent ubiquitin-mediated proteolysis and promotes muscle atrophy. MAFbx transcript is abundant in cardiac and skeletal muscle undergoing atrophy. MAFbx -/- mice are resistant to muscle atrophy. MAFbx is thought to recognize and bind to some phosphorylated proteins and promote their ubiquitination and degradation during skeletal muscle atrophy. It interacts with MyoD by ubiquitination via a sequence found in transcriptional coactivators and therefore may play an important role in the course of muscle differentiation by determining the abundance of MyoD. MAFbx is specifically expressed in cardiac and skeletal muscle. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: human Fbx32 1-200aa |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 41 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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