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Anti-FNTB Antibody (1O812)
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Catalog No. TMAC-01525
Alias Ras proteins prenyltransferase subunit beta, Protein farnesyltransferase subunit beta, FTase-beta, EC 2.5.1.58, CAAX farnesyltransferase subunit beta
Anti-FNTB Antibody (1O812) is a Rabbit antibody targeting FNTB. Anti-FNTB Antibody (1O812) can be used in WB,ICC/IF.
Anti-FNTB Antibody (1O812)
Anti-FNTB Antibody (1O812)
😃Good
Catalog No. TMAC-01525Alias Ras proteins prenyltransferase subunit beta, Protein farnesyltransferase subunit beta, FTase-beta, EC 2.5.1.58, CAAX farnesyltransferase subunit beta
Anti-FNTB Antibody (1O812) is a Rabbit antibody targeting FNTB. Anti-FNTB Antibody (1O812) can be used in WB,ICC/IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $296 | 7-10 days | |
| 100 μL | $496 | 7-10 days |
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Antigen Details
Chemical Properties
| Description | Anti-FNTB Antibody (1O812) is a Rabbit antibody targeting FNTB. Anti-FNTB Antibody (1O812) can be used in WB,ICC/IF. |
| Synonyms | Ras proteins prenyltransferase subunit beta, Protein farnesyltransferase subunit beta, FTase-beta, EC 2.5.1.58, CAAX farnesyltransferase subunit beta |
| Ig Type | IgG |
| Clone | 1O812 |
| Reactivity | Human,Rat |
| Verified Activity | 1. Western blot analysis of FNTB on K562 cells lysates using anti-FNTB antibody at 1/1,000 dilution. 2. ICC staining FNTB in JAR cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Mammalian protein farnesyl transferases are heterodimeric proteins containing two nonidentical α and β subunits that attach farnesyl residues to a cysteine at the fourth position from the COOH terminus of several proteins, including nuclear lamins and p21Ras proteins. The natural substrates contain the Cys-A-A-Xaa recognition sequence, where the A residues are aliphatic and Xaa represents methionine, serine, glutamine or cysteine. The purified farnesyl transferase is an a-b heterodimer. The β subunit, which is known as FTβ, CAAX farnesyltransferase subunit β, or Ras proteins prenyltransferase subunit β, is a 437 amino acid protein that contains five PFTB repeats and binds the peptide substrate. The α subunit is suspected to participate in formation of a stable complex with the substrate farnesyl pyrophosphate. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 43 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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