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Anti-MITF Antibody (9E208)
(Synonyms: WS2A, WS2, MITF-A, Microphthalmia-associated transcription factor, MI, COMMAD, CMM8, Class E basic helix-loop-helix protein 32(bHLHe32), BHLHE32) Copy Product Info
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Synonyms: WS2A, WS2, MITF-A, Microphthalmia-associated transcription factor, MI, COMMAD, CMM8, Class E basic helix-loop-helix protein 32(bHLHe32), BHLHE32
Catalog No. TMAC-02589 Copy Product Info
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Anti-MITF Antibody (9E208) is a Rabbit antibody targeting MITF. Anti-MITF Antibody (9E208) can be used in FCM,ICC,WB.
Anti-MITF Antibody
(9E208)
(9E208)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $297 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Stability & Storage
| Description | Anti-MITF Antibody (9E208) is a Rabbit antibody targeting MITF. Anti-MITF Antibody (9E208) can be used in FCM,ICC,WB. |
| Synonyms | WS2A, WS2, MITF-A, Microphthalmia-associated transcription factor, MI, COMMAD, CMM8, Class E basic helix-loop-helix protein 32(bHLHe32), BHLHE32 |
| Ig Type | IgG |
| Clone | 9E208 |
| Reactivity | Human,Mouse,Rat |
| Application | |
| Recommended Dose | WB: 1:1000-2000; ICC: 1:100-500; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | MITF (microphthalmia-associated transcription factor) is a melanocytic nuclear protein that contains basic helix-loop-helix (HLH) and leucine zipper (LZ) domains. These protein motifs are frequently observed in other transcription factors and are particularly common to members of the Myc family. MITF can directly associate with DNA as a homodimer and is required for the development and differentiation of melanocytes. Its expression is upregulated by cAMP and cAMP-dependent pathways. MITF activates several different gene promoters by binding to their E-boxes. Tyrosinase, TRP1 and TRP2 are pigment synthesis genes activated by MITF. When MITF is phosphorylated on Ser73 (via the MAPK pathway), it associates with co-activators of the p300/CBP family and enhances transcription. MITF has several isoforms including MITF-M which is specifically expressed in melanocytes. In MITF-deficient mice there is a complete absence of melanocytes. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 55 kDa. |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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