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Anti-XAF1 Antibody (6H309)

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Catalog No. TMAC-04293

Anti-XAF1 Antibody (6H309) is a Mouse antibody targeting XAF1. Anti-XAF1 Antibody (6H309) can be used in WB,IP,IF.

Anti-XAF1 Antibody (6H309)

Anti-XAF1 Antibody (6H309)

😃Good
Catalog No. TMAC-04293
Anti-XAF1 Antibody (6H309) is a Mouse antibody targeting XAF1. Anti-XAF1 Antibody (6H309) can be used in WB,IP,IF.
Pack SizePriceAvailabilityQuantity
50 μL$2977-10 days
100 μL$4267-10 days
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Product Introduction

Bioactivity
Description
Anti-XAF1 Antibody (6H309) is a Mouse antibody targeting XAF1. Anti-XAF1 Antibody (6H309) can be used in WB,IP,IF.
Reactivity
Human
Application
Recommended Dose
WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate)
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundX-linked inhibitor of apoptosis protein (XIAP)-associated factor 1 (XAF1) is azinc finger protein that blocks the apoptotic activity of XIAP. XIAP is amember of the family of intrinsic inhibitors of apoptosis proteins (IAPs), whichsuppress apoptosis through the inhibition of caspases. In the presence ofXAF1, XIAP protein redistributes from the cytosol to the nucleus. XAF1 transcripts(3.9-, 4.5-, 6.0- and 7.0-kb) are present at high levels in heart and ovary.Low expression of XAF1 mRNA is an indicator for certain cancers (WM164melanoma, WM35 melanoma, U937 pro-monocytic leukemia and HT1080fibrosarcoma), suggesting that low levels of XAF1 transcript may enhancecancer cell-survival through the relative increase in XIAP apoptotic function.IFN-α and IFN-β activate the human XAF1 gene, which maps to chromosome17p13.1.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Amino acids 1-225 mapping at the N-terminus of XAF1 of human origin
Antigen Species
human
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 35 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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