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Anti-XAF1 Antibody (6H309)
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Catalog No. TMAC-04293
Alias XIAP-associated factor 1, XIAPAF1, XIAP associated factor 1, XAF1_HUMAN, XAF 1, HSXIAPAF1, HSXIAPAF 1, BIRC4BP, BIRC4-binding protein, BIRC4 binding protein, BIRC 4 binding protein
Anti-XAF1 Antibody (6H309) is a Mouse antibody targeting XAF1. Anti-XAF1 Antibody (6H309) can be used in WB,IP,IF.
Anti-XAF1 Antibody (6H309)
Anti-XAF1 Antibody (6H309)
😃Good
Catalog No. TMAC-04293Alias XIAP-associated factor 1, XIAPAF1, XIAP associated factor 1, XAF1_HUMAN, XAF 1, HSXIAPAF1, HSXIAPAF 1, BIRC4BP, BIRC4-binding protein, BIRC4 binding protein, BIRC 4 binding protein
Anti-XAF1 Antibody (6H309) is a Mouse antibody targeting XAF1. Anti-XAF1 Antibody (6H309) can be used in WB,IP,IF.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 50 μL | $297 | 7-10 days | |
| 100 μL | $426 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-XAF1 Antibody (6H309) is a Mouse antibody targeting XAF1. Anti-XAF1 Antibody (6H309) can be used in WB,IP,IF. |
| Synonyms | XIAP-associated factor 1, XIAPAF1, XIAP associated factor 1, XAF1_HUMAN, XAF 1, HSXIAPAF1, HSXIAPAF 1, BIRC4BP, BIRC4-binding protein, BIRC4 binding protein, BIRC 4 binding protein |
| Clone | 6H309 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of XAF1 expression in non-transfected (A) and human XAF1 transfected (B) 293T whole cell lysates. |
| Application | |
| Recommended Dose | WB: 1:100-1000; IP: 1-2 μg per 100-500 μg of total protein(1 ml of cell lysate) |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | X-linked inhibitor of apoptosis protein (XIAP)-associated factor 1 (XAF1) is azinc finger protein that blocks the apoptotic activity of XIAP. XIAP is amember of the family of intrinsic inhibitors of apoptosis proteins (IAPs), whichsuppress apoptosis through the inhibition of caspases. In the presence ofXAF1, XIAP protein redistributes from the cytosol to the nucleus. XAF1 transcripts(3.9-, 4.5-, 6.0- and 7.0-kb) are present at high levels in heart and ovary.Low expression of XAF1 mRNA is an indicator for certain cancers (WM164melanoma, WM35 melanoma, U937 pro-monocytic leukemia and HT1080fibrosarcoma), suggesting that low levels of XAF1 transcript may enhancecancer cell-survival through the relative increase in XIAP apoptotic function.IFN-α and IFN-β activate the human XAF1 gene, which maps to chromosome17p13.1. |
| Conjucates | Unconjugated |
| Immunogen | Amino acids 1-225 mapping at the N-terminus of XAF1 of human origin |
| Antigen Species | human |
| Uniprot ID |
| Molecular Weight | Theoretical: 35 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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For example, your dosage is 10 mg/kg Each animal weighs 20 g, and the dosage volume is 100 μL . 
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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