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Anti-SIRT2 Antibody (2G702)
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Catalog No. TMAC-03762
Alias Sirtuin type 2, Sirtuin 2, Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae), SIRT2_HUMAN, SIRT 2, SIR2-like protein 2, SIR2L2, SIR2L, SIR2, S. cerevisiae, homolog-loke 2, Sir2 related protein type 2, SIR2 like protein 2, SIR2, Silent information regulator 2, Silencing information regulator 2 like, Regulatory protein SIR2 homolog 2, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-2, NAD dependent deacetylase sirtuin 2, FLJ37491, FLJ35621
Anti-SIRT2 Antibody (2G702) is a Rabbit antibody targeting SIRT2. Anti-SIRT2 Antibody (2G702) can be used in FCM,ICC/IF,IP.
Anti-SIRT2 Antibody (2G702)
Anti-SIRT2 Antibody (2G702)
😃Good
Catalog No. TMAC-03762Alias Sirtuin type 2, Sirtuin 2, Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae), SIRT2_HUMAN, SIRT 2, SIR2-like protein 2, SIR2L2, SIR2L, SIR2, S. cerevisiae, homolog-loke 2, Sir2 related protein type 2, SIR2 like protein 2, SIR2, Silent information regulator 2, Silencing information regulator 2 like, Regulatory protein SIR2 homolog 2, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-2, NAD dependent deacetylase sirtuin 2, FLJ37491, FLJ35621
Anti-SIRT2 Antibody (2G702) is a Rabbit antibody targeting SIRT2. Anti-SIRT2 Antibody (2G702) can be used in FCM,ICC/IF,IP.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $497 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-SIRT2 Antibody (2G702) is a Rabbit antibody targeting SIRT2. Anti-SIRT2 Antibody (2G702) can be used in FCM,ICC/IF,IP. |
| Synonyms | Sirtuin type 2, Sirtuin 2, Sirtuin (silent mating type information regulation 2 homolog) 2 (S.cerevisiae), SIRT2_HUMAN, SIRT 2, SIR2-like protein 2, SIR2L2, SIR2L, SIR2, S. cerevisiae, homolog-loke 2, Sir2 related protein type 2, SIR2 like protein 2, SIR2, Silent information regulator 2, Silencing information regulator 2 like, Regulatory protein SIR2 homolog 2, NAD-dependent protein deacetylase sirtuin-2, NAD-dependent deacetylase sirtuin-2, NAD dependent deacetylase sirtuin 2, FLJ37491, FLJ35621 |
| Ig Type | IgG |
| Clone | 2G702 |
| Reactivity | Human,Mouse,Rat |
| Verified Activity | 1. ICC staining SIRT2 in 293 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 2. ICC staining SIRT2 in PC-12 cells (green). The nuclear counter stain is DAPI (blue). Cells were fixed in paraformaldehyde, permeabilised with 0.25% Triton X100/PBS. 3. Flow cytometric analysis of Hela cells with SIRT2 antibody at 1/50 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black). Alexa Fluor 488-conjugated goat anti rabbit IgG was used as the secondary antibody.    |
| Application | |
| Recommended Dose | ICC/IF: 1:50-200; FCM: 1:50-100 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | The silent information regulator (SIR2) family of genes are highly conserved from prokaryotes to eukaryotes and are involved in diverse processes, including transcriptional regulation, cell cycle progression, DNA-damage repair and aging. In S. cerevisiae, Sir2p deacetylates histones in a NAD-dependent manner, which regulates silencing at the telomeric, rDNA and silent mating-type loci. Sir2p is the founding member of a large family, designated sirtuins, which contain a conserved catalytic domain. The human homologs, which include SIRT1-7, are divided into four main branches: SIRT1-3 are class I, SIRT4 is class II, SIRT5 is class III and SIRT6-7 are class IV. SIRT proteins may function via mono-ADP-ribosylation of proteins. SIRT2 contains a 323 amino acid catalytic core domain with a NAD-binding domain and a large groove which is the likely site of catalysis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 43 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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