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Anti-ELAVL1 Antibody (3D917)

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Catalog No. TMAC-02077
Alias HUR, Hu-antigen R (HuR), ELAV-like protein 1, ELAVL1

Anti-ELAVL1 Antibody (3D917) is a Rabbit antibody targeting ELAVL1. Anti-ELAVL1 Antibody (3D917) can be used in WB,IHC,IP,FCM.

Anti-ELAVL1 Antibody (3D917)

Anti-ELAVL1 Antibody (3D917)

😃Good
Catalog No. TMAC-02077Alias HUR, Hu-antigen R (HuR), ELAV-like protein 1, ELAVL1
Anti-ELAVL1 Antibody (3D917) is a Rabbit antibody targeting ELAVL1. Anti-ELAVL1 Antibody (3D917) can be used in WB,IHC,IP,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-ELAVL1 Antibody (3D917) is a Rabbit antibody targeting ELAVL1. Anti-ELAVL1 Antibody (3D917) can be used in WB,IHC,IP,FCM.
SynonymsHUR, Hu-antigen R (HuR), ELAV-like protein 1, ELAVL1
Ig Type
IgG
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of HuR/ELAVL1 on different lysates using anti-HuR/ELAVL1 antibody at 1/1,000 dilution. POSITIVE CONTROL: Lane 1: Rat spleen tissue, Lane 2: Rat heart tisse, Lane 3: PC-12, Lane 4: Mouse heart tissue, Lane 5: Hela.
2. Immunohistochemical analysis of paraffin-embedded rat lung tissue using anti-HuR/ELAVL1 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human colon cancer tissue using anti-HuR/ELAVL1 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded human breast tissue using anti-HuR/ELAVL1 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded mouse testis tissue using anti-HuR/ELAVL1 antibody. Counter stained with hematoxylin.
6. Immunohistochemical analysis of paraffin-embedded mouse heart tissue using anti-HuR/ELAVL1 antibody. Counter stained with hematoxylin.
7. Flow cytometric analysis of Jurkat cells with HuR/ELAVL1 antibody at 1/100 dilution (red) compared with an unlabelled control (cells without incubation with primary antibody; black).
Application
Recommended Dose
WB: 1:500-2000; IHC: 1:100-500; IP: 1:10-50; FCM: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundRNA-binding protein that binds to the 3'-UTR region of mRNAs and increases their stability. Involved in embryonic stem cells (ESCs) differentiation: preferentially binds mRNAs that are not methylated by N6-methyladenosine (m6A), stabilizing them, promoting ESCs differentiation. Binds to poly-U elements and AU-rich elements (AREs) in the 3'-UTR of target mRNAs. Binds avidly to the AU-rich element in FOS and IL3/interleukin-3 mRNAs. In the case of the FOS AU-rich element, binds to a core element of 27 nucleotides that contain AUUUA, AUUUUA, and AUUUUUA motifs. Binds preferentially to the 5'-UUUU[AG]UUU-3' motif in vitro. With ZNF385A, binds the 3'-UTR of p53/TP53 mRNA to control their nuclear export induced by CDKN2A. Hence, may regulate p53/TP53 expression and mediate in part the CDKN2A proliferative activity. May also bind with ZNF385A the CCNB1 mRNA.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc

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