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Anti-FOXA2 Antibody (8N555)
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Catalog No. TMAC-01532
Alias Transcription factor 3B(TCF-3B), HNF-3-beta, HNF3B, TCF3B, HNF-3B, Hepatocyte nuclear factor 3-beta, FOXA 2, Forkhead box protein A2
Anti-FOXA2 Antibody (8N555) is a Rabbit antibody targeting FOXA2. Anti-FOXA2 Antibody (8N555) can be used in ICC/IF,WB.
Anti-FOXA2 Antibody (8N555)
Anti-FOXA2 Antibody (8N555)
😃Good
Catalog No. TMAC-01532Alias Transcription factor 3B(TCF-3B), HNF-3-beta, HNF3B, TCF3B, HNF-3B, Hepatocyte nuclear factor 3-beta, FOXA 2, Forkhead box protein A2
Anti-FOXA2 Antibody (8N555) is a Rabbit antibody targeting FOXA2. Anti-FOXA2 Antibody (8N555) can be used in ICC/IF,WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $298 | 7-10 days | 7-10 days | |
| 100 μL | $498 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-FOXA2 Antibody (8N555) is a Rabbit antibody targeting FOXA2. Anti-FOXA2 Antibody (8N555) can be used in ICC/IF,WB. |
| Synonyms | Transcription factor 3B(TCF-3B), HNF-3-beta, HNF3B, TCF3B, HNF-3B, Hepatocyte nuclear factor 3-beta, FOXA 2, Forkhead box protein A2 |
| Ig Type | IgG |
| Clone | 8N555 |
| Reactivity | Human |
| Verified Activity | 1. Western blot analysis of FOXA2 on HT-29 cells lysates using anti-FOXA2 antibody at 1/500 dilution.  |
| Application | |
| Recommended Dose | WB: 1:1000-5000; ICC/IF: 1:50-200 |
| Antibody Type | Monoclonal |
| Host Species | Rabbit |
| Construction | Recombinant Antibody |
| Purification | ProA affinity purified |
| Appearance | Liquid |
| Formulation | 1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide. |
| Research Background | Transcription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally discribed as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein |
| Uniprot ID |
| Molecular Weight | Theoretical: 52 kDa. |
Stability & Storage
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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