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Anti-FOXA2 Antibody (8N555) (Synonyms: Transcription factor 3B(TCF-3B), HNF-3-beta, HNF3B, TCF3B, HNF-3B, He...)

Catalog No. TMAC-01532 Copy Product Info
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Anti-FOXA2 Antibody (8N555) is a Rabbit antibody targeting FOXA2. Anti-FOXA2 Antibody (8N555) can be used in ICC/IF,WB.

Anti-FOXA2 Antibody (8N555)

Copy Product Info
🥰Excellent
Catalog No. TMAC-01532
Synonyms Transcription factor 3B(TCF-3B), HNF-3-beta, HNF3B, TCF3B, HNF-3B, Hepatocyte nuclear factor 3-beta, FOXA 2, Forkhead box protein A2

Anti-FOXA2 Antibody (8N555) is a Rabbit antibody targeting FOXA2. Anti-FOXA2 Antibody (8N555) can be used in ICC/IF,WB.

Anti-FOXA2 Antibody
(8N555)
Pack SizePriceUSA StockGlobal StockQuantity
50 μL$2987-10 days7-10 days
100 μL$4987-10 days7-10 days
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction

Bioactivity
Description
Anti-FOXA2 Antibody (8N555) is a Rabbit antibody targeting FOXA2. Anti-FOXA2 Antibody (8N555) can be used in ICC/IF,WB.
SynonymsTranscription factor 3B(TCF-3B), HNF-3-beta, HNF3B, TCF3B, HNF-3B, Hepatocyte nuclear factor 3-beta, FOXA 2, Forkhead box protein A2
Ig Type
IgG
Clone
8N555
Reactivity
Human
Verified Activity
1. Western blot analysis of FOXA2 on HT-29 cells lysates using anti-FOXA2 antibody at 1/500 dilution.
verifiedActivity
Application
Recommended Dose
WB: 1:1000-5000; ICC/IF: 1:50-200
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundTranscription factor that is involved in embryonic development, establishment of tissue-specific gene expression and regulation of gene expression in differentiated tissues. Is thought to act as a 'pioneer' factor opening the compacted chromatin for other proteins through interactions with nucleosomal core histones and thereby replacing linker histones at target enhancer and/or promoter sites. Binds DNA with the consensus sequence 5'-[AC]A[AT]T[AG]TT[GT][AG][CT]T[CT]-3' (By similarity). In embryonic development is required for notochord formation. Involved in the development of multiple endoderm-derived organ systems such as the liver, pancreas and lungs; FOXA1 and FOXA2 seem to have at least in part redundant roles. Originally discribed as a transcription activator for a number of liver genes such as AFP, albumin, tyrosine aminotransferase, PEPCK, etc. Interacts with the cis-acting regulatory regions of these genes. Involved in glucose homeostasis; regulates the expression of genes important for glucose sensing in pancreatic beta-cells and glucose homeostasis. Involved in regulation of fat metabolism. Binds to fibrinogen beta promoter and is involved in IL6-induced fibrinogen beta transcriptional activation.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 52 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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