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Anti-HSF4 Antibody (1L976)

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Catalog No. TMAC-02026

Anti-HSF4 Antibody (1L976) is a Mouse antibody targeting HSF4. Anti-HSF4 Antibody (1L976) can be used in WB,FCM.

Anti-HSF4 Antibody (1L976)

Anti-HSF4 Antibody (1L976)

😃Good
Catalog No. TMAC-02026
Anti-HSF4 Antibody (1L976) is a Mouse antibody targeting HSF4. Anti-HSF4 Antibody (1L976) can be used in WB,FCM.
Pack SizePriceAvailabilityQuantity
50 μL$2987-10 days
100 μL$4287-10 days
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Product Introduction

Bioactivity
Description
Anti-HSF4 Antibody (1L976) is a Mouse antibody targeting HSF4. Anti-HSF4 Antibody (1L976) can be used in WB,FCM.
Reactivity
Human
Application
Recommended Dose
WB: 1:500-1000; FCM: 1:100-200
Antibody Type
Monoclonal
Host SpeciesMouse
ConstructionHybridoma Monoclonal Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, Preservative: 0.05% Sodium Azide.
Research BackgroundHeat shock transcription factors (HSF, also designated HSTF) 1 and 2 are involved in this regulation. HSF1 and HSF2 are upregulated by estrogen, at both the mRNA and protein level. HSF1 is normally found as a monomer, whose transcriptional activity is repressed by constitutive phosphorylation. Upon activation, HSF1 forms trimers, gains DNA binding activity and is translocated to the nucleus. HSF2 activity is associated with differentiation and development, and, like HSF1, binds DNA as a trimer. HSF4 exists as two splice variants and is expressed in heart, brain and skeletal muscle as a homotrimer. HSF4a does not contain a DNA-binding domain and inhibits the formation of HSF1 nuclear bodies, thus repressing HSF1 mediated transcription. HSF4b does contain a DNA-binding domain and colocalizes with HSF1 nuclear bodies after heat shock.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Antigen Species
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 53 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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