Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Lenalidomide-4-OH is a cereblon (CRBN) ligand derived from Lenalidomide, utilized in the recruitment of the CRBN protein. It can be conjugated to the protein ligand via a linker, facilitating the formation of PROTAC.
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Description | Lenalidomide-4-OH is a cereblon (CRBN) ligand derived from Lenalidomide, utilized in the recruitment of the CRBN protein. It can be conjugated to the protein ligand via a linker, facilitating the formation of PROTAC. |
In vitro | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
Molecular Weight | 260.25 |
Formula | C13H12N2O4 |
CAS No. | 1061604-41-8 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
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Lenalidomide-4-OH 1061604-41-8 Lenalidomide 4 OH Lenalidomide4OH inhibitor inhibit