Anti-FTO Antibody (6A98)

Name: Anti-FTO Antibody (6A98)
Brand: TargetMol
SKU: TMAC-01569
Rating: 4.5 (1 reviews)

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Catalog No. TMAC-01569

Anti-FTO Antibody (6A98) is a Rabbit antibody targeting FTO. Anti-FTO Antibody (6A98) can be used in WB,ICC/IF,IHC.

Anti-FTO Antibody (6A98)

😃Good

Catalog No. TMAC-01569

Anti-FTO Antibody (6A98) is a Rabbit antibody targeting FTO. Anti-FTO Antibody (6A98) can be used in WB,ICC/IF,IHC.

Pack Size	Price	Availability	Quantity
50 μL	$298	7-10 days
100 μL	$496	7-10 days

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Product Introduction

Bioactivity

Description	Anti-FTO Antibody (6A98) is a Rabbit antibody targeting FTO. Anti-FTO Antibody (6A98) can be used in WB,ICC/IF,IHC.
Ig Type	IgG
Clone	6A98
Reactivity	Human
Verified Activity	1. Western blot analysis of FTO on different lysates using anti-FTO antibody at 1/1,000 dilution. Positive control: Lane 1: Human fetal brain tissue, Lane 2: HepG2, Lane 3: 293. 2. Immunohistochemical analysis of paraffin-embedded human pancreas tissue using anti-FTO antibody. Counter stained with hematoxylin.
Application	WB ICC/IF IHC
Recommended Dose	WB: 1:500-2000; IHC: 1:50-200; ICC/IF: 1:50-200
Antibody Type	Monoclonal
Host Species	Rabbit
Construction	Recombinant Antibody
Purification	ProA affinity purified
Appearance	Liquid
Formulation	1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research Background	FTO, also known as Fatso or KIAA1752, is a 505 amino acid protein that has an N-terminal nuclear localization signal. Expressed in a variety of tissues, with highest levels present in brain and pancreatic tissue, Fatso exists as four alternatively spliced isoforms, one of which is associated with a predisposition to childhood and adult obesity. Due to its involvement in the development of obesity, Fatso is associated with an increased BMI and may be involved in the pathogenesis of type 2 diabetes. The gene encoding Fatso maps to human chromosome 16, which encodes over 900 genes and comprises nearly 3% of the human genome. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, as is Crohn's disease, which is a gastrointestinal inflammatory condition.

Related Conjugates and Formulations

Conjucates

Unconjugated

Antigen Details

Immunogen	Recombinant Protein
Uniprot ID	Q9C0B1

Chemical Properties

Stability & Storage

Stability & Storage	Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
Transport	Shipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc