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Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) (Synonyms: ZTNFR9, TRICKB, TRICK2A, TRICK2, TRAILR2, TRAIL rec...)
Catalog No. TMAH-01187 Copy Product Info
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Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) is an antibody targeting TRAIL R2/DR5/TNFRSF10B. Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) can be used in ELISA,IF,WB.
Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303)
Copy Product Info🥰Excellent
Catalog No. TMAH-01187
Synonyms ZTNFR9, TRICKB, TRICK2A, TRICK2, TRAILR2, TRAIL receptor 2, TRAIL R2, TNFRSF10B, KILLER/DR5, KILLER, Fas-like protein, DR5TRICK2B, DR5, CD262
Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) is an antibody targeting TRAIL R2/DR5/TNFRSF10B. Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) can be used in ELISA,IF,WB.
Anti-TRAIL R2/DR5/TNFRSF10B Antibody
(2E303)
(2E303)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 50 μL | $209 | 7-10 days | 7-10 days | |
| 100 μL | $348 | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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| Description | Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) is an antibody targeting TRAIL R2/DR5/TNFRSF10B. Anti-TRAIL R2/DR5/TNFRSF10B Antibody (2E303) can be used in ELISA,IF,WB. |
| Synonyms | ZTNFR9, TRICKB, TRICK2A, TRICK2, TRAILR2, TRAIL receptor 2, TRAIL R2, TNFRSF10B, KILLER/DR5, KILLER, Fas-like protein, DR5TRICK2B, DR5, CD262 |
| Ig Type | hIgG1 |
| Clone | 2E303 |
| Reactivity | Human |
| Verified Activity | 1. Western Blot -Positive WB detected in: Hela whole cell lysate, HepG2 whole cell lysate, A549 whole cell lysate, U251 whole cell lysate -All lanes: TNFRSF10B antibody at 1:500 -Secondary: Goat polyclonal to Human IgG at 1/50000 dilution -Predicted band size: 13 kDa -Observed band size: 13 kDa 2. Immunofluorescence staining of Hela cell with TMAH-01187 at 1:50, counter-stained with DAPI. The cells were fixed in 4% formaldehyde and blocked in 10% normal Goat Serum. The cells were then incubated with the antibody overnight at 4°C. The secondary antibody was FITC-conjugated AffiniPure Goat Anti-Human IgG(H+L). |
| Application | |
| Recommended Dose | WB:1:500-1:2000; IF:1:50-1:200. |
| Antibody Type | Monoclonal |
| Subcellular Localization | Membrane; Single-pass type I membrane protein. |
| Tissue Specificity | Widely expressed in adult and fetal tissues; very highly expressed in tumor cell lines such as HeLaS3, K-562, HL-60, SW480, A-549 and G-361; highly expressed in heart, peripheral blood lymphocytes, liver, pancreas, spleen, thymus, prostate, ovary, uterus, |
| Construction | Recombinant Antibody |
| Purification | Affinity-chromatography |
| Appearance | Liquid |
| Formulation | Preservative: 0.03% Proclin 300. Constituents: 50% Glycerol, 0.01M PBS, PH 7.4. |
| Research Background | Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B. Essential for ER stress-induced apoptosis. |
| Conjucates | Unconjugated |
| Immunogen | Recombinant Protein: Human TNFRSF10B Protein |
| Antigen Species | Human |
| Gene Name | TNFRSF10B |
| Gene ID | |
| Uniprot ID | |
| Biology Area | Cancer, Cardiovascular, Cell biology, Signal transduction |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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