Tris Buffered Saline, composed of Tris and NaCl, is a commonly used buffer reagent in molecular biology. It regulates pH and ionic strength, making it integral to applications like DNA/RNA extraction, PCR, and protein electrophoresis. It aids in purifying and protecting nucleic acids, enhancing reaction efficiency and concentration. In protein electrophoresis, it stabilizes the gel and maintains pH levels. Overall, Tris Buffered Saline is valued for its versatility, solubility, and low toxicity in molecular biology applications.