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Anti-DDX6 Antibody (4T946)

😃Good
Catalog No. TMAC-01134
Alias RCK, Probable ATP-dependent RNA helicase DDX6, Oncogene RCK, HLR2, EC 3.6.4.13, DEAD box protein 6, ATP-dependent RNA helicase p54

Anti-DDX6 Antibody (4T946) is a Rabbit antibody targeting DDX6. Anti-DDX6 Antibody (4T946) can be used in WB,IHC.

Anti-DDX6 Antibody (4T946)

Anti-DDX6 Antibody (4T946)

😃Good
Catalog No. TMAC-01134Alias RCK, Probable ATP-dependent RNA helicase DDX6, Oncogene RCK, HLR2, EC 3.6.4.13, DEAD box protein 6, ATP-dependent RNA helicase p54
Anti-DDX6 Antibody (4T946) is a Rabbit antibody targeting DDX6. Anti-DDX6 Antibody (4T946) can be used in WB,IHC.
Pack SizePriceAvailabilityQuantity
50 μL$2967-10 days
100 μL$4977-10 days
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Product Introduction

Bioactivity
Description
Anti-DDX6 Antibody (4T946) is a Rabbit antibody targeting DDX6. Anti-DDX6 Antibody (4T946) can be used in WB,IHC.
SynonymsRCK, Probable ATP-dependent RNA helicase DDX6, Oncogene RCK, HLR2, EC 3.6.4.13, DEAD box protein 6, ATP-dependent RNA helicase p54
Ig Type
IgG
Clone
4T946
Reactivity
Human,Mouse,Rat
Verified Activity
1. Western blot analysis of DDX6 on different lysates using anti-DDX6 antibody at 1/500 dilution.Positive control:Lane 1: Human colon, Lane 2: SH-SY-5Y, Lane 3: SiHa, Lane 4: K562.
2. Immunohistochemical analysis of paraffin-embedded human tonsil tissue using anti-DDX6 antibody. Counter stained with hematoxylin.
3. Immunohistochemical analysis of paraffin-embedded human kidney tissue using anti-DDX6 antibody. Counter stained with hematoxylin.
4. Immunohistochemical analysis of paraffin-embedded mouse small intestine tissue using anti-DDX6 antibody. Counter stained with hematoxylin.
5. Immunohistochemical analysis of paraffin-embedded rat brain tissue using anti-DDX6 antibody. Counter stained with hematoxylin.
Application
Recommended Dose
WB: 1:500-1000; IHC: 1:50-100
Antibody Type
Monoclonal
Host SpeciesRabbit
ConstructionRecombinant Antibody
PurificationProA affinity purified
AppearanceLiquid
Formulation1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.
Research BackgroundRCK, also known as DDX6 and P54, is a member of the DEAD-box RNA helicase family of proteins, all of which share common protein motifs. Found in most tissues, RCK is an unwindase that exhibits ATP-dependent RNA un-winding activity, as well as the ability to decay RNA in the 5'-3' direction. In non-malignant cells, RCK is associated with all processes of normal RNA metabolism including splicing, export and translation initiation. Mutations in the gene encoding RCK can cause the protein to be overexpressed, changing its function to that of an oncogene that positively regulates the expression of genes involved in cell growth and proliferation. It is believed that, through its unwindase activity, the main function of RCK is to downregulate mRNA expression and maintain normal transcriptional levels within the cell.
Related Conjugates and Formulations
Conjucates
Unconjugated
Antigen Details
Immunogen
Recombinant Protein
Uniprot ID
Chemical Properties
Molecular WeightTheoretical: 54 kDa.
Stability & Storage
Stability & StorageStore at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
TransportShipping with blue ice.

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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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